摘要
嗜酸细胞性胃肠炎是一种较少见的慢性消化道疾病,以胃肠组织中嗜酸性粒细胞浸润、胃肠壁增厚为特征,其病因及发病机制不明。该病临床表现多种多样,可伴或不伴外周血嗜酸性粒细胞升高,影像学表现为局部肠管壁增厚、腹腔积液,内镜可表现为黏膜充血、糜烂、溃疡等,依据病理活检中嗜酸性粒细胞的浸润数量确诊。由于该病的临床表现、辅助检查等缺乏特异性,病理诊断标准仍不规范,临床诊断仍较困难,本文通过对该病临床表现、治疗进展等方面做一综述,以期提高临床医师对该病的认识。
Eosinophilic gastroenteritis is a relatively rare chronic gastrointestinal disease, which is characterized by eosinophil infiltration in gastrointestinal tissues and thickening of gastrointestinal wall. Its etiology and pathogenesis remain unknown. The clinical manifestations of the disease are diverse, with or without the elevated peripheral blood eosinophil. The images can show local intestinal wall thickening and peritoneal effusion, and the endoscopy can show mucosal congestion, erosion, ulcer, etc. The diagnosis was made according to the number of eosinophil infiltration in pathological biopsy. Due to the lack of specificity in clinical manifestations and auxiliary examinations of the disease, the pathological diagnostic criteria are still not standardized, and the clinical diagnosis is still difficult. The clinical manifestations and treatment progress of the disease are reviewed in this article, so as to improve clinicians’ understanding of the disease.
作者
吴金容
宋正己
WU Jinrong;SONG Zhengji(Department of Gastroenterology,the First People’s Hospital of Yunnan Province,Yunnan,Kunming 650032,China)
出处
《中国医药科学》
2022年第13期48-51,93,共5页
China Medicine And Pharmacy
基金
国家自然科学基金(81760110)。
关键词
嗜酸细胞性胃肠炎
临床表现
诊断
内科治疗
Eosinophilic gastroenteritis
Clinical manifestation
Diagnosis
Medical treatment
