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外周血阴性的嗜酸性粒细胞胃肠炎内镜及病理18例分析 被引量:5

Endoscopic and pathological analysis of eosinophilic gastroenteritis with negative peripheral blood in 18 cases
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摘要 目的:探讨外周血阴性的嗜酸性粒细胞胃肠炎的诊断及治疗。方法:收治腹痛患者18例,通过临床症状、胃镜活检及病理明确诊断。结果:在18例患者中,2例(11.1%)合并肠梗阻,8例(44.4%)有恶心、呕吐症状,16例(88.8%)黏膜层型,2例(11.1%)肌层型。内镜下表现为黏膜充血、水肿,片状糜烂、浅溃疡,病理发现嗜酸性粒细胞浸润,18例患者均因药物治疗效果不佳行胃镜检查明确诊断,给予糖皮质激素治疗后症状缓解。结论:嗜酸性粒细胞胃肠炎临床表现复杂多样,外周血阴性的嗜酸性粒细胞胃肠炎更容易误诊、漏诊,当遇到不明原因反复发作腹痛时,排除其他因素,要考虑此病,需要行胃镜检查进一步明确诊断。 Objective:To explore the diagnosis and treatment of eosinophilic gastroenteritis with negative peripheral blood.Methods:18 patients with abdominal pain were selected.They were diagnosed by clinical symptoms,endoscopic biopsy andpathology.Results:In the 18 patients,2 cases(11.1%) were complicated with intestinal obstruction;8 cases(44.4%) had nausea andvomiting;16 cases(88.8% ) were the mucosal layer type;2 cases(11.1% ) were the muscular layer type.The main endoscopicmanifestations were mucosal congestion,edema,flake erosion,shallow ulcers,and eosinophilic infiltration was found in pathology.18patients were diagnosed by gastroscopy due to poor drug effects,and the symptoms were relieved after glucocorticoid therapy.Conclusion:The clinical manifestations of eosinophilic gastroenteritis were complicated.The eosinophilic gastroenteritis withnegative peripheral blood was more likely to be misdiagnosed and missed.When doctors encountered unexplained recurrentabdominal pain,after exclusion of other factors,doctors had to consider the disease,and the patients need to be diagnosed bygastroscopy.
作者 崔轶 胡艳艳 Cui Yi;Hu Yanyan(Department of Gastroenterology,the Third People's Hospital of Zhengzhou City,Henan Province 450000)
出处 《中国社区医师》 2016年第22期153-153,155,共2页 Chinese Community Doctors
关键词 外周血阴性 嗜酸性粒细胞胃肠炎 胃镜 病理 Negative peripheral blood Eosinophilic gastroenteritis Gastroscopy Pathology
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