摘要
胃癌在全球的发病率及死亡率分别位列恶性肿瘤第5位和第4位。早期胃癌临床症状易被忽略,确诊时大部分患者已达晚期。但在伴有远处转移的晚期胃癌患者中,有一部分为单一远处转移,如仅有腹膜游离癌细胞阳性的腹膜转移、肝转移、卵巢转移、骨及骨髓转移、腹主动脉旁淋巴结转移以及肺转移等。单一远处转移不同于广泛转移,通过对转移灶选择最优的治疗方案,如转移灶手术切除、手术联合围手术期化疗、除手术外的其他局部治疗、靶向治疗以及免疫治疗等,可以获得优于广泛转移胃癌患者的长期生存获益。本文将对单一远处转移的晚期胃癌治疗现状与进展作一综述。
Gastric cancer is the fifth most common malignancy and the fourth leading cause of cancer-related mortality worldwide.The clinical symptoms of early gastric cancer are easy to be ignored.Most of the patients are advanced gastric cancer at the time of diagnosis,who cannot receive surgery with shorter survival time.However,in this part of patients with distant metastasis,some of them are gastric cancer with single distant metastasis,such as gastric cancer with positive peritoneal cytology,liver metastasis,ovarian metastasis,bone and/or marrow metastasis,para-aortic lymph node metastasis and lung metastasis.Choosing appropriate treatment strategy for gastric cancer patients with single distant metastasis,such as metastasectomy,perioperative chemotherapy,other local therapy,targeted therapy and immunotherapy,will offer a long-term survival benefit than those with extensive metastases.The purpose of this article is to review the current situation and progress in the treatment of advanced gastric cancer with single distant metastasis.
作者
丁怡心
边晓倩
孙丽斌
齐卫卫
DING Yixin;BIAN Xiaoqian;SUN Libin;QI Weiwei(Department of Oncology,the Affiliated Hospital of Qingdao University,Qingdao 266031,China)
出处
《临床肿瘤学杂志》
CAS
2022年第7期647-654,共8页
Chinese Clinical Oncology
关键词
胃癌
单发转移
治疗
Gastric cancer
Single distant metastasis
Treatment
