摘要
目的 探究128例不孕症患者行多胎减胎术(MPR)对妊娠期并发症、妊娠结局、新生儿出生结局的影响。方法 选取行多胎减胎术的128例不孕症患者作为实验组,按照减胎后保留胎儿数,分为保留单胎组84例和保留双胎组44例;另选取同期因不孕症助孕的单胎和双胎患者共128例作为对照组,分为对照单胎组84例和对照双胎组44例,分析4组患者妊娠期并发症、妊娠结局及新生儿出生结局。结果 保留双胎组及对照双胎组间妊娠期糖尿病、妊娠期高血压疾病、胎膜早破发生率分别为13. 64%、18. 18%、13. 64%和11. 36%、11. 36%、4. 54%,均高于保留单胎组、对照单胎组,而平均分娩孕周低于保留单胎组、对照单胎组(P <0. 05)。保留双胎组流产率高于其他3组,活产率低于其他3组(P <0. 05)。保留双胎组及对照双胎组早产、低出生体重分别为40. 9%、43. 18%和36. 36%、31. 81%,新生儿畸形及死亡发生率均高于保留单胎组、对照单胎组,而平均出生体重低于保留单胎组、对照单胎组(P <0. 05)。保留单胎组与对照单胎组间、保留双胎组与对照双胎组间母婴结局差异无统计学意义(P> 0. 05)。结论 多胎减胎术可改善多胎妊娠的母婴结局,保留胎儿数是影响妊娠期并发症和母婴结局的重要因素。
Objective To analyze the effect of multifetal pregnancy reduction(MFPR)on pregnancy complications,pregnancy outcomes and neonatal birth outcomes.Methods 128 cases of infertile patients who underwent MFPR were retrospectively selected as the experimental group.According to the number of retained embryos after MFPR,the pregnancy reduction group was divided into the retained twin group(n=44)and the retained singleton group(n=84).128 women who assisted pregnancy in the same period were collected as control group,including twin group(n=44)and singleton group(n=84).The pregnancy complications,pregnancy outcomes and neonatal birth outcomes were compared among the four groups.Results The incidence rates of gestational diabetes,pregnancy-induced hypertension,premature rupture of membranes in the retained twin group(13.64%,18.18%,13.64%,respectively)and regular twin group(11.36%,11.36%,4.54%,respectively)were higher than that in retained single and regular single groups,but the average gestational week of delivery was lower than that in the latter groups(P<0.05).The incidence rate of premature delivery was higher than those in the other three groups,but the live birth rate was lower than the other three groups(P<0.05).The incidence rates of premature delivery,low birth weight,neonatal deformities and neonatal mortality in retained twin group (40.9%,43.18%) and regular twin group (36.36%,31.81%) were higher than that in retained twin and regular singleton groups ( P <0.05).There was no significant difference in maternal and infant outcomes between the retained singleton group and regular singleton group. Conclusion MFPR can improve the maternal and infant outcome of multiple pregnancies.The number of retained embryos after MFPR is an important factor affecting pregnancy complications and maternal and infant outcomes.
作者
康卉娴
王莉莉
张燕
姚海蓉
石冬梅
杜娟
郝苗苗
包俊华
KANG Huixian;WANG Lili;ZHANG Yan;YAO Hairong;SHI Dongmei;DU Juan;HAO Miaomiao;BAO Junhua(Maternal and Child Health Hospital of Yinchan,Yinchuan 750001,China;General Hospital of Ningxia Medical University,Yinchuan 750004,China)
出处
《宁夏医学杂志》
CAS
2022年第7期620-623,共4页
Ningxia Medical Journal
基金
宁夏自然科学基金资助项目(NZ14250)。
关键词
减胎术
妊娠期并发症
妊娠结局
新生儿出生结局
Multifetal pregnancy reduction
Pregnancy complications
Pregnancy outcomes
Neonatal birth outcomes
