摘要
目前异性性传播是艾滋病主要的传播方式,而注射吸毒人群因其特殊的行为方式是艾滋病防治的另一重要人群,通过查阅文献了解艾滋病经异性性传播和注射吸毒传播的流行及接受抗病毒治疗现状,并探讨影响治疗效果的因素,为进一步提高我国异性性传播和注射吸毒HIV/AIDS抗病毒治疗效果和生存质量提供参考依据。HIV/AIDS治疗依从性、基线CD4^(+)T细胞计数、不良反应及耐药的产生是影响抗病毒治疗的影响因素。今后应继续扩大艾滋病检测范围,早发现、早治疗,通过定期监测病毒载量、CD4^(+)T细胞计数及临床评估来提高患者依从性,制定个性化的治疗方案,以提高生存质量,降低病死率。
The heterosexual transmission is the main way of HIV infection at the moment,and the injecting drug users are another important group for HIV prevention and treatment,due to their special behavioral pattern.The epidemic and antiretroviral therapy(ART)status of HIV/AIDS transmitted by heterosexual transmission and injecting drugs are understand through literature review,and the influencing factors of treatment effect are discussed,so as to provide reference for improving the treatment effect and the quality of life of HIV/AIDS persons transmitted by heterosexual transmission and injecting drugs in China.The adherence of ART,baseline of CD4^(+)T cell count,adverse reaction and drug resistance are the influencing factors to the antiviral treatment.In future,the detection scope of HIV/AIDS should be expanded for early finding and early treatment.Through regular monitoring of viral load,CD4^(+)T cell count and clinical assessment to increase the adherence of patients and formulate the personalized therapeutic schedule,so as to improve the quality of life and decrease the fatality rate.
作者
阿热祖·肉孜呢亚孜
胡晓敏
倪明健
Arezu ROUZINIYAZI;HU Xiao-min;NI Ming-jian(不详;College of Public Health,Xinjiang Medical University,Urumqi,830011)
出处
《疾病预防控制通报》
2022年第3期84-89,共6页
Bulletin of Disease Control & Prevention(China)
基金
国家科技重大专项(2018ZX10715-007)
新疆艾滋病防控研究重点实验室(XJYS1706)。
