摘要
目的 探究瑞芬太尼复合丙泊酚用于开胸手术的麻醉效果。方法 54例实施开胸手术的患者,按随机抽数方式分为研究组(单数)和对照组(双数),每组27例。研究组使用瑞芬太尼复合丙泊酚诱导麻醉,对照组仅采用丙泊酚诱导麻醉。比较两组患者不同时间段(插管后1、5 min)平均动脉压(MAP)和心率(HR),不同时间段(术后2、8、12、24 h)视觉模拟评分法(VAS)评分,术后恢复情况(术后自主呼吸恢复时间、苏醒时间、拔管时间),不良反应(血压下降、心率不齐、呼吸抑制及其他)发生情况。结果 研究组插管后1、5 min的平均动脉压和心率均低于对照组,差异具有统计学意义(P<0.05)。研究组患者术后自主呼吸恢复时间(9.61±3.32)min、苏醒时间(8.31±4.25)min、拔管时间(10.26±3.78)min均短于对照组的(18.61±6.32)、(12.44±5.25)、(19.36±6.89)min,差异具有统计学意义(P<0.05)。术后8、12、24 h,研究组VAS评分均低于对照组,差异具有统计学意义(P<0.05)。研究组不良反应发生率3.70%低于对照组的25.93%,差异具有统计学意义(P<0.05)。结论 将瑞芬太尼复合丙泊酚用于开胸手术麻醉中,可有效提升镇痛效果,缩短患者术后恢复时间,且不良反应小,具有较高的推广价值。
Objective To investigate the anesthesia effect of remifentanil combined with propofol on thoracotomy.Methods A total of 54 patients who underwent thoracotomy were randomly divided into research group(odd number)and control group(even number),with 27 cases in each group.The research group received remifentanil combined with propofol for anesthesia induction,and the control group only received propofol for anesthesia induction.Both groups were compared in terms of mean arterial pressure(MAP)and heart rate(HR)at different time periods(1,5 min after intubation),and the visual analogue scale(VAS)scores at different time periods(2,8,12,and 24 h after surgery),postoperative recovery(postoperative recovery time of spontaneous breathing,recovery time,extubation time),occurrence of adverse reactions(blood pressure drop,arrhythmia,respiratory depression and others).Results The mean arterial pressure and heart rate at 1 and 5 min after intubation in the research group were lower than those in the control group,and the difference was statistically significant(P<0.05).The postoperative recovery time of spontaneous breathing(9.61±3.32)min,recovery time(8.31±4.25)min,and extubation time(10.26±3.78)min of the research group were shorter than(18.61±6.32),(12.44±5.25),and(19.36±6.89)min of the control group,and the difference was statistically significant(P<0.05).At 8,12,and 24 h after surgery,the VAS scores of the research group were lower than those of the control group,and the difference was statistically significant(P<0.05).Conclusion Remifentanil combined with propofol in anesthesia of thoracotomy can effectively improve the analgesic effect,shorten the time required for postoperative recovery of patients,with less adverse reactions,which has high promotion value.
作者
裴莹莹
PEI Ying-ying(Xingcheng People's Hospital,Xingcheng 125100,China)
出处
《中国实用医药》
2022年第13期93-95,共3页
China Practical Medicine
关键词
瑞芬太尼
丙泊酚
开胸手术麻醉
效果
Remifentanil
Propofol
Anesthesia in thoracotomy
Effect
