摘要
目的探讨老年腹部手术患者应用七氟醚对术后认知功能的影响。方法回顾性分析2019年1月—2020年1月老年腹部手术治疗100例患者,根据麻醉方式不同分组,每组50例。对照组采取异丙酚维持麻醉,观察组实施了七氟醚麻醉。比较两组麻醉的时间、手术过程出血总量、平均拔管时间以及疼痛评分、麻醉优良率、不良反应、不同时间老年腹部手术患者认知功能MMSE评分。结果观察组麻醉的时间、手术过程出血总量、平均拔管时间以及疼痛评分(123.26±12.11)min、(416.21±44.52)mL、(17.11±4.56)min、(3.21±1.03)分和对照组(123.31±12.13)min、(416.42±44.26)mL、(17.31±4.15)min、(3.12±1.08)分,差异无统计学意义(t=0.424、1.043、0.145、0.735,P>0.05)。观察组麻醉优良率100.00%和对照组100.00%,差异无统计学意义(χ^2=0.000,P>0.05)。观察组不良反应和对照组差异无统计学意义(χ^2=0.000,P>0.05。其中,两组均有1例(2%)出现血压过高,降压后恢复正常。术后1 d和术后3 d观察组老年腹部手术患者认知功能MMSE评分(21.21±0.21)分、(24.01±0.21)分低于对照组(25.41±0.44)分、(26.01±0.33)分(t=9.721、9.245,P<0.05)。结论老年腹部手术患者应用七氟醚对术后短时间内的认知功能有一定影响,但随着时间延长,其影响逐渐消退。
Objective To investigate the effect of sevoflurane on postoperative cognitive function in elderly patients undergoing abdominal surgery. Methods A retrospective analysis of 100 elderly patients undergoing abdominal surgery from January 2019 to January 2020 was divided into two groups according to different anesthesia methods, with 50 cases in each group. The control group was given propofol to maintain anesthesia, and the observation group was given sevoflurane anesthesia. The time of anesthesia, total blood loss during the operation, average extubation time, pain score, excellent anesthesia rate, adverse reactions, and MMSE scores of cognitive function in elderly abdominal surgery patients at different times were compared between the two groups. Results Observation group anesthesia time, total blood loss during surgery,average extubation time and pain score(123.26±12.11)min,(416.21±44.52)mL,(17.11±4.56)min,(3.21±1.03)points and control group(123.31 ±12.13) min,(416.42 ±44.26)mL,(17.31 ±4.15)min,(3.12 ±1.08)minutes, the difference was not statistically significant(t=0.424, 1.043, 0.145, 0.735, P>0.05). The excellent and good rate of anesthesia in the observation group was100.00% and the control group was 100.00%, the difference was not statistically significant(χ^2=0.000, P>0.05). There was no statistically significant difference in adverse reactions between the observation group and the control group(χ^2=0.000, P>0.05. Among them, 1 case(2%) in both groups had hypertension, which returned to normal after lowering the blood pressure.1 day after surgery and surgery The cognitive function MMSE score(21.21±0.21)points and(24.01±0.21)points of the elderly patients with abdominal surgery in the observation group were lower than the control group(25.41±0.44)points and(26.01±0.33) points(t=9.721, 9.245, P<0.05). Conclusion The use of sevoflurane in elderly patients with abdominal surgery has a certain effect on the cognitive function in a short period of time after surgery, but the effect gradually fades w
作者
景卫
刘卫
魏丕红
张龙明
JING Wei;LIU Wei;WEI Pi-hong;ZHANG Long-ming(Department of Anesthesiology,Tai'an Central Hospital,Tai'an,Shandong Province,271000 China;Operating Room,Tai'an Central Hospital,Tai'an,Shandong Province,271000 China)
出处
《中外医疗》
2020年第25期23-25,共3页
China & Foreign Medical Treatment
基金
山东省泰安市科技发展计划项目:食管癌患者胸腔镜手术期间局部脑氧饱和度变化与其对患者认知功能水平的影响(2019NS84)。
关键词
老年
腹部手术患者
七氟醚
术后认知功能
影响
Elderly
Patients with abdominal surgery
Sevoflurane
Postoperative cognitive function
Impact
