摘要
目的:了解精神专科医院门诊失眠症患者第二类精神药品使用情况及挖掘门诊失眠症患者对第二类精神药品产生依赖的相关因素。方法:采用横断面研究方法,以2021年7月—2021年12月我院门诊就诊的失眠症患者为研究对象,经培训医师逐项填写自编的第二类精神药品使用情况调查表,获得有效调查问卷525份。数据采用SPSS21.0软件统计,对第二类精神药品使用情况及产生依赖的影响因素进行分析。结果:共调查患者525例,男205例(39.05%),女320例(60.95%),平均年龄(53.98±14.91)岁,慢性失眠障碍410例(78.10%),短期失眠障碍45例(8.57%),其他失眠障碍70例(13.33%);第二类精神药品按使用比例高低依次为阿普唑仑(22.29%),氯硝西泮(18.48%),劳拉西泮(17.52%);服用第二类精神药品的持续时间:(54.43±25.67)个月。共筛出依赖者51例,进行Logistic回归分析,结果示与家人关系、经历重大事件、酒精依赖、依从性、随诊是产生药物依赖的影响因素(P<0.05)。结论:1.失眠患者普遍选择了第二类精神药品治疗,且服用时间偏长,存在部分药物依赖患者。2.对于存在药物依赖危险因素的失眠症患者,给予该类药物治疗时应慎重。
Objective: To investigate the use of class II psychotropic drugs in out-patient insomnia patients of psychiatric hospital and explore the related factors of dependence on class Ⅱ psychotropic drugs in out-patient insomnia patients.Methods: Using a cross-sectional study method, the patients with insomnia in the outpatient department of our hospital from July 2021 to December 2021 were selected as the subjects. The trained physicians filled in the questionnaire of the use of class Ⅱ psychotropic drugs item by item, and 525 valid questionnaires were obtained. SPSS21.0 software was used to analyze the use of category Ⅱ psychotropic drugs and the influencing factors of dependence. Results: A total of 525 patients were investigated, 205 males(39.05%), 320 females(60.95%), average age(53.98±14.91) years old, 410 chronic insomnia disorders(78.10%), 45 short-term insomnia disorders(8.57%), 70 other insomnia disorders(13.33%). The second category of psychotropic drugs were alprazolam(22.29%), clonazepam(18.48%), lorazepam(17.52%). Duration of taking class Ⅱpsychotropic drugs:54.43±25.67 months. A total of 51 dependent patients were screened and logistic regression analysis was conducted. The results showed that family relationship, experience of major events, alcohol dependence, compliance and follow-up were the influencing factors of drug dependence(P<0.05). Conclusion: 1. Insomnia patients generally choose the second type of psychotropic drugs for treatment, and take them for a long time, and there are some drug-dependent patients. 2. For insomnia patients with risk factors of drug dependence, such drug treatment should be cautious.
作者
王晓
黄元
支晓慧
刘召英
孙波
常桂花
王国伟
孙振晓
王志广
WANG Xiao;HUANG Yuan;ZHI Xiaohui;LIU Zhaoying;SUN Bo;CHANG Guihua;WANG Guowei;SUN Zhenxiao;WANG Zhiguang(Department of Pharmacy,LinyiMunicipal Mental Health Center,Linyi 276005,Shandong,China;Department of Drug Abuse Monitoring,Shandong Adverse Drug Reaction Monitoring Center,Ji'nan 250014,Shandong,China;Department of psychiatry,LinyiMunicipal Mental Health Center,Linyi 276005,Shandong,China)
出处
《中国药物滥用防治杂志》
CAS
2022年第5期557-563,共7页
Chinese Journal of Drug Abuse Prevention and Treatment
基金
山东省药物滥用监测哨点研究课题(编号:药械化-2021-SDADRKY17)。
关键词
精神专科医院
门诊
失眠症
第二类精神药品
依赖
Psychiatric hospital
Outpatient department
Insomnia
ClassⅡpsychotropic drugs
Dependence
