摘要
目的探讨乳腺癌术后切口感染病原学特点及术后切口感染发生的相关因素。方法回顾性分析2016年5月至2021年4月在重庆大学附属三峡医院行乳腺癌保乳手术治疗的200例中老年患者临床病例资料,分析感染患者病原菌和药敏试验结果,探讨影响乳腺癌术后切口感染发生的影响因素。结果200例中老年患者年龄为55~75岁,乳腺癌保乳手术患者中,13例术后发生切口感染(4.64%)。共分离40株病原菌,革兰阳性菌14株、革兰阴性菌25株、真菌1例。单因素和多因素Logistic回归分析显示,患者年龄(OR=3.40)、手术时间(OR=2.50)、白蛋白水平(OR=2.83)、合并基础疾病(OR=4.23)、预防性使用抗菌药物(OR=3.14)及住院时间(OR=2.33)是导致乳腺癌术后切口感染发生的独立危险因素(均P<0.05)。结论乳腺癌患者保乳手术后发生切口感染常见病原菌为革兰阴性菌,术后切口感染影响因素众多,临床需采取针对性措施减少或预防术后切口感染发生。
Objective To explore the pathogenic characteristics of incision wound infections after breast cancer surgery and related influencing factors.Methods Clinical files of 200 middle-aged and elderly patients who underwent breast-conserving surgery for breast cancer in the Affiliated Three Gorges Hospital from May 2016 to April 2021 were retrospectively analyzed.The results of pathogenic bacteria and drug sensitivity tests were examined,and the influencing factors of postoperative incision infections after breast cancer surgery were analyzed.Results Among 200 middle-aged and elderly patients aged 55-75 years who underwent breast-conserving surgery for breast cancer,13 patients(4.64%)developed postoperative incision infections,with 40 strains of pathogenic bacteria isolated,including 14 strains of gram-positive bacteria,25 strains of gram-negative bacteria and 1 fungal strain.Univariate and multivariate logistic regression analysis showed that age(OR=3.40),duration of surgery(OR=2.50),albumin level(OR=2.83),underlying diseases(OR=4.23),preventive use of antibiotics(OR=3.14)and length of hospital stay(OR=2.33)were independent risk factors for postoperative incision infections in breast cancer patients(all P<0.05).Conclusions Common pathogens of incision infections after breast-conserving surgery are Gram-negative bacteria.There are many factors affecting postoperative incision infections.Clinical measures need to be taken to reduce or prevent postoperative incision infections.
作者
熊鑫
刘微微
应雪艳
何培生
高朝卫
Xiong Xin;Liu Weiwei;Ying Xueyan;He Peisheng;Gao Chaowei(Department of Breast Surgery,Three Gorges Hospital Affiliated to Chongqing University,Chongqing 404000,China)
出处
《中华老年医学杂志》
CAS
CSCD
北大核心
2022年第6期700-703,共4页
Chinese Journal of Geriatrics
关键词
乳腺肿瘤
外科伤口感染
Breast neoplasms
Surgical wound infection
