摘要
目的探讨心功能不全合并贫血患者发生急性心肌梗死的相关疾病因素。方法选取2018年1月至2020年12月于首都医科大学附属北京安贞医院住院的心功能不全合并贫血患者3040例,根据是否发生急性心肌梗死分为急性心肌梗死组(322例)和非急性心肌梗死组(2718例)。比较2组患者年龄、性别、合并疾病等临床资料,分析患者发生急性心肌梗死的疾病因素。结果急性心肌梗死组年龄、合并糖尿病、高血压、高脂血症、肾脏病、消化道出血比例均高于非急性心肌梗死组[(68±12)岁比(59±15)岁、53.1%(171/322)比24.5%(666/2718)、70.5%(227/322)比53.5%(1454/2718)、59.6%(192/322)比26.0%(706/2718)、58.7%(189/322)比30.1%(817/2718)、15.2%(49/322)比5.5%(149/2718)],合并心房颤动、瓣膜病比例均低于非急性心肌梗死组[14.6%(47/322)比19.4%(527/2718)、27.0%(87/322)比54.5%(1480/2718)],差异均有统计学意义(均P<0.10)。Logistic回归分析结果显示,年龄≥60岁、合并糖尿病、高脂血症、肾脏病、消化道出血是心功能不全合并贫血患者发生急性心肌梗死的独立危险因素(均P<0.05)。结论在心功能不全合并贫血患者中,年龄≥60岁患者合并有糖尿病、高脂血症、肾脏病、消化道出血时更容易发生急性心肌梗死。
Objective To explore the characteristics of acute myocardial infarction in patients with cardiac insufficiency complicated with anemia. Methods Totally 3 040 patients with cardiac insufficiency complicated with anemia admitted to Beijing Anzhen Hospital, Capital Medical University from January 2018 to December 2020 were selected. According to whether acute myocardial infarction developed, patients were divided into acute myocardial infarction group(322 cases) and non acute myocardial infarction group(2 718 cases). The clinical data such as age, gender and combined diseases were compared between the two groups, and the influencing factors of acute myocardial infarction were analyzed. Results Age, the proportions of diabetes mellitus, hypertension, hyperlipidemia, kidney disease and gastrointestinal bleeding in acute myocardial infarction group were higher than those in non acute myocardial infarction group[(68±12) years vs(59±15) years, 53.1%(171/322) vs 24.5%(666/2 718), 70.5%(227/322) vs 53.5%(1 454/2 718), 59.6%(192/322) vs 26.0%(706/2 718), 58.7%(189/322) vs 30.1%(817/2 718), 15.2%(49/322) vs 5.5%(149/2 718)], the proportions of atrial fibrillation and valvular disease in acute myocardial infarction group were lower than those in non acute myocardial infarction group[14.6%(47/322) vs 19.4%(527/2 718), 27.0%(87/322) vs 54.5%(1 480/2 718)], and the differences were statistically significant(all P<0.10). Logistic regression analysis showed that age ≥60 years, diabetes mellitus, hyperlipidemia, kidney disease and gastrointestinal bleeding were independent risk factors for acute myocardial infarction in patients with cardiac insufficiency complicated with anemia(all P<0.05). Conclusion In patients with heart failure complicated with anemia, those age ≥60 years are more likely to develop acute myocardial infarction when they have diabetes mellitus, hyperlipidemia, kidney disease and gastrointestinal bleeding.
作者
高杰
冯妍
王以新
陈婉萍
卢淑立
靳相公
曲星
Gao Jie;Feng Yan;Wang Yixin;Chen Wanping;Lu Shuli;Jin Xianggong;Qu Xing(Department of General Medical,Beijying Anzhen Hospital,Capital Medical University,Bejing 100029,China;College of General Medicine and Continuing Education,Capital Medical Universiry,Beijing 100069,China)
出处
《中国医药》
2022年第4期501-504,共4页
China Medicine
基金
国家自然科学基金(81703932)
北京市医院管理中心青年人才培养“青苗”计划(QML20190605)
北京市中医管理局中医药科技发展资金项目(JJ-2020-01)
北京市朝阳区科技计划项目(CYSF2027)。
关键词
心功能不全
贫血
急性心肌梗死
合并疾病
Cardiac insufficiency
Anemia
Acute myocardial infarction
Combined diseases
