摘要
目的:观察针刺疗法联合解郁通窍汤治疗精神分裂症的临床疗效。方法:将102例精神分裂症患者随机分为治疗组与对照组各51例。对照组给予氯丙嗪治疗,治疗组在对照组的基础上给予针刺联合解郁通窍汤治疗。治疗1个月后,统计分析2组临床疗效和不良反应发生情况,并对2组治疗前后阳性和阴性症状量表(PANSS)、阴性症状量表(SANS)、汉密尔顿抑郁量表(HAMD)及生活质量综合评定量表(GQOLI-74)进行评分比较。结果:治疗组总有效率为96.08%,对照组为78.43%,2组比较,差异有统计学意义(P<0.05)。治疗前,2组PANSS量表中阳性症状、阴性症状、一般病理评分及总分比较,差异无统计学意义(P>0.05);治疗后,2组阳性症状、阴性症状、一般病理评分及总分均较治疗前降低(P<0.05);且治疗组阴性症状、一般病理评分及总分均低于对照组(P<0.05),而2组阳性症状评分差别不大(P>0.05)。治疗前,2组SANS、HAMD评分比较,差异无统计学意义(P>0.05);治疗后,2组SANS、HAMD评分均较治疗前降低(P<0.05),且治疗组SANS、HAMD评分低于对照组(P<0.05)。治疗前,2组GQOLI-74评分比较,差异无统计学意义(P>0.05);治疗后,2组GQOLI-74评分均较治疗前升高(P<0.05),且治疗组GQOLI-74评分高于对照组(P<0.05)。治疗组不良反应发生率为5.88%,对照组为19.61%,2组比较,差异有统计学意义(P<0.05)。结论:针刺加解郁通窍汤联合氯丙嗪治疗精神分裂症,能提高临床疗效,有效改善患者临床症状和抑郁状态,提高生活质量,减少不良反应。
Objective:To observe the clinical effect of acupuncture therapy combined with Jieyu Tongqiao tang for schizophrenia.Methods:A total of 102 cases of patients with schizophrenia were randomly divided into the treatment group and the control group,51 cases in each group.The control group was given chloropromazine,and the treatment group was additionally given acupuncture combined with Jieyu Tongqiao tang based on the treatment of the control group.After onemonth treatment,statistical analysis of clinical effect and incidence of adverse reactions in the two groups was carried out.Before and after treatment,scores of Positive and Negative Syndrome Scale(PANSS),Scale for Assessment of Negative Symptoms(SANS),Hamilton Depression Scale(HAMD),and Generic Quality of Life Inventory-74(GQOLI-74)were compared between the two groups.Results:The total effective rate was 96.08%in the treatment group and 78.43%in the control group,the difference being significant(P<0.05).Before treatment,when compared scores of positive symptoms,negative symptoms,and general pathology of PANSS,as well as the total scores between the two groups,there was no significance being found in the difference(P>0.05).After treatment,scores of positive symptoms,negative symptoms,and general pathology,as well as the total scores in the two groups were decreased when compared with those before treatment(P<0.05);scores of negative symptoms and general pathology,as well as the total score in the treatment group were lower than those in the control group(P<0.05);there was no significant difference being found in the comparison of scores of positive symptoms between the two groups(P>0.05).Before treatment,there was no significant difference being found in the comparison of scores of SANS and HAMD between the two groups(P>0.05).After treatment,scores of SANS and HAMD in the two groups were decreased when compared with those before treatment(P<0.05),and the two scores in the treatment group were lower than those in the control group(P<0.05).Before treatment,there wa
作者
许彬彬
林定艺
赵娜
XU Binbin;LIN Dingyi;ZHAO Na
出处
《新中医》
CAS
2022年第8期174-178,共5页
New Chinese Medicine
基金
温州市科技局基础性医疗卫生科技项目(Y20180863)。
关键词
精神分裂症
解郁通窍汤
针刺疗法
氯丙嗪
阳性和阴性症状量表
阴性症状量表
Schizophrenia
Jieyu Tongqiao tang
Acupuncture therapy
Chloropromazine
Positive and Negative Syndrome Scale
Scale for Assessment of Negative Symptoms
