摘要
目的研究分析血清降钙素原测定在急诊发热患者诊断中的应用价值。方法选取2020年9月—2021年9月在该院急诊治疗的发热患者90例为研究对象,根据免疫学与病原学诊断结果分组,组别为甲组(n=45,细菌感染)、乙组(n=45,非细菌感染)。所有患者均给予血常规检查、血清C反采应蛋白与降钙素原检测,对两组检查检测结果以及各指标阳性率进行统计比较,同时计算各指标对细菌感染诊断的敏感度、特异度、阳性预测值、阴性预测值。结果甲组中性粒细胞、白细胞、C反应蛋白、降钙素原水平分别为(80.21±8.13)%、(11.94±2.81)×10^(9)/L、(17.12±3.89)mg/L、(1.26±0.45)ng/mL,均高于乙组(66.18±7.21)%、(9.11±2.46)×10^(9)/L、(10.01±3.24)mg/L、(0.41±0.13)ng/mL,差异有统计学意义(t=8.661、5.083、9.421、12.173,P<0.05)。甲组中性粒细胞、白细胞、C反应蛋白、降钙素原阳性率分别为82.22%、80.00、82.22%、95.56%,均高于乙组46.67%、33.33%、37.78%、15.56%,差异有统计学意义(P<0.05);降钙素原诊断敏感度、特异度、阳性预测值、阴性预测值分别为95.56%、84.44%、86.00%、95.00%,明显高于中性粒细胞、白细胞、C反应蛋白诊断,差异有统计学意义(P<0.05)。结论血清降钙素原测定在急诊发热患者诊断中的应用价值非常高,有助于病因学的鉴别诊断,敏感度与特异度较高。
Objective To study and analyze the application value of serum procalcitonin in the diagnosis of emergency fever patients.Methods A total of 90 fever patients treated in the emergency department of the hospital from September 2020 to September 2021 were selected as the research objects.According to the results of immunological and etiological diagnosis,the groups were group A(n=45,bacterial infection)and group B(n=45,non-bacterial infection).All patients were given blood routine examination,serum C-reactive protein and procalcitonin detection.Statistical comparison was made between the two groups of test results and the positive rate of each index.At the same time,the sensitivity,specificity,positive predictive value and negative predictive value of each index for the diagnosis of bacterial infection were calculated.Results The levels of neutrophils,leukocytes,C-reactive protein and procalcitonin in group A were(80.21±8.13)%,(11.94±2.81)×10^(9)/L,(17.12±3.89)mg/L,(1.26±0.45)ng/mL,was higher than that of group B(66.18±7.21)%,(9.11±2.46)×10^(9)/L,(10.01±3.24)mg/L,(0.41±0.13)ng/mL,the difference was statistically significant(t=8.661,5.083,9.421,12.173,P<0.05).The positive rates of neutrophils,leukocytes,C-reactive protein,and procalcitonin in group A were 82.22%,80.00%,82.22%and 95.56%,of the group A 46.67%,33.33%,37.78%,and 15.56%,the difference was statistically significant(P<0.05);the diagnostic sensitivity,specificity,positive predictive value,and negative predictive value of procalcitonin were 95.56%,84.44%,86.00%,and 95.00%,re spectively,significantly higher than the diagnosis of neutrophils,leukocytes and C-reactive protein,the difference was statistically significant(P<0.05).Conclusion The value of serum procalcitonin in the diagnosis of emergency fever patients is very high,and it is helpful for the differential diagnosis of etiology.It has high sensitivity and specificity.
作者
裴越
佘皓
PEI Yue;SHE Hao(Department of Laboratory,Yixing Hospital of Traditional Chinese Medicine,Yixing,Jiangsu Province,214200 China;Department of Emergency,Yixing Hospital of Traditional Chinese Medicine,Yixing,Jiangsu Province,214200 China)
出处
《系统医学》
2022年第9期76-79,共4页
Systems Medicine
关键词
急诊
发热
降钙素原
诊断价值
Emergency
Fever
Procalcitonin
Diagnostic value
