摘要
目的探讨以科普的手段提高南平地区癫痫患者对于血药浓度监测的认识,通过个体化用药,更好的控制癫痫发作,减低癫痫患者的发作次数。方法设计一项随机、对照实验,选取本院62例前来就诊确诊为癫痫患者,随机分成科普组30例、对照组32例。对照组常规进行服药指导,科普组进行科普宣教。根据血药浓度监测结果,使用精准药学方式给患者制定个体化干预方案。结果本研究显示科普组患者六个月后的血药浓度监测数、血药浓度达窗数明显高于对照组,且发作次数低于对照组。结论以科普的手段可提高南平地区癫痫患者对于血药浓度监测的认识,减少患者的发作次数,可较好的控制癫痫发作。
OBJECTIVE This study investigated the use of science popularization to increase awareness of therapeutic drug monitoring in epilepsy patients in Nanping,to better control seizures and reduce the number of seizures in epilepsy patients through individualized medication administration.METHODS A randomized,controlled trial was designed in this study.62 patients presenting to the hospital with confirmed epilepsy were selected and randomly divided into 30 patients in the science group and 32 patients in the control group.The control group was routinely instructed to take medication,while the science group was educated on science.Patients are given individualised intervention plans using a precision pharmacy approach based on the results of therapeutic drug monitoring.RESULTS This study showed that patients in the science group had a significantly higher number of therapeutic drug monitoring,a higher number of Serum concentration reaching the therapeutic window at six months and a lower number of episodes than the control group.CONCLUSION This study found that the use of scientology can improve the awareness of therapeutic drug monitoring and reduce the number of seizures in patients with epilepsy in Nanping,which can better control seizures.
作者
郑玲
廖凯君
陆冬丽
冯艳
姜政华
刘銮妹
ZHENG Ling;LIAO Kai-jun;LU Dong-li;FENG Yan;JIANG Zheng-hua;LIU Luan-mei(Department of Pharmacy,Nanping First Hospital Affiliated to Fujian Medical University,Nanping 353000,China)
出处
《海峡药学》
2022年第5期81-84,共4页
Strait Pharmaceutical Journal
关键词
丙戊酸钠
血药浓度监测
科普干预
药学服务
Sodium valproate
Therapeutic drug monitoring
Scientific interventions
Pharmaceutical services
