摘要
目的探究低频重复经颅磁刺激配合认知康复训练治疗癫痫的效果。方法选择2022年4月—2023年5月本院收治的70例癫痫患者为研究对象。随机将其分为对照组和观察组,各35例。对照组予以认知康复训练,观察组在对照组基础上联合低频重复经颅磁刺激,两组均治疗1个月。对比两组的氧化应激指标、癫痫发作频率、生活质量、认知功能。结果观察组癫痫发生频率为(1.02±0.08)次/月,低于对照组的(1.86±0.14)次/月,差异有统计学意义(P<0.05)。治疗后,观察组简易精神状态检查量表评分为(22.49±2.11)分,蒙特利尔认知评估量表评分为(22.15±1.32)分,均高于对照组的(19.44±1.17)分、(18.07±1.13)分,组间差异有统计学意义(P<0.05)。治疗后,观察组一氧化氮、丙二醛水平均低于对照组,总抗氧化能力高于对照组,组间差异有统计学意义(P<0.05)。治疗后,观察组生活质量各维度评分均高于对照组,组间差异有统计学意义(P<0.05)。结论低频重复经颅磁刺激配合认知康复训练治疗癫痫,能够有效改善患者的癫痫发作,提高患者认知功能与生活质量,改善氧化应激反应。
Objective To explore the effects of low-frequency repetitive transcranial magnetic stimulation combined with cognitive rehabilitation training in patients with epilepsy.Methods A total of 70 epilepsy patients admitted to our hospital from April 2022 to May 2023 were selected as the research subjects,they were randomly divided into a control group and an observation group,with 35 cases in each group.The control group received cognitive rehabilitation training,and the observation group combined with low-frequency repetitive transcranial magnetic stimulation on the basis of the control group,both groups were treated for 1 month.The oxidative stress parameters,seizure frequency,quality of life,and cognitive function were compared between the two groups.Results The frequency of epilepsy occurrence in the observation group was(1.02±0.08)times/month,which was lower than(1.86±0.14)times/month in the control group,the difference was statistically significant(P<0.05).After treatment,the scores of Mini-Mental State Eexamination Scale was(22.49±2.11)points and the scores of Montreal Cognitive Assessment Scale was(22.15±1.32)points in the observation group were higher than(19.44±1.17)points and(18.07±1.13)points in the control group,the difference were statistically significant between the two groups(P<0.05).After treatment,the nitric oxide and malondialdehyde in the observation group were lower than those in the control group,and the total antioxidant capacity was higher than that in the control group,the difference were statistically significant between the two groups(P<0.05).After treatment,the scores of all dimensions of quality of life in the observation group were higher than those in the control group,and the differences were statistically significant between the two groups(P<0.05).Conclusion Low-frequency repetitive transcranial magnetic stimulation combined with cognitive rehabilitation training in the treatment of epilepsy,which can effectively improve seizures,enhance cognitive function and quality of life,an
作者
杜燕
DU Yan(Department of Rehabilitation Medicine,The 960th Hospital of the Chinese People's Liberation Army Joint Logistic Support Force,Jinan 250000,China)
出处
《反射疗法与康复医学》
2024年第9期28-31,共4页
Reflexology And Rehabilitation Medicine
关键词
癫痫
低频重复经颅磁刺激
认知康复训练
癫痫发作频率
认知功能
氧化应激
生活质量
Epilepsy
Low-frequency repetitive transcranial magnetic stimulation
Cognitive rehabilitation training
Epilepsy frequency
Cognitive function
Oxidative stress
Quality of life
