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化痰通络汤联合阿司匹林对急性脑梗死患者认知功能及神经功能的影响

Effects of Huatan Tongluo Decoction Combined with Aspirin on Cognitive Function and Nervous Function in Patients with Acute Cerebral Infarction
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摘要 目的探讨化痰通络汤联合阿司匹林对急性脑梗死患者认知功能及神经功能的影响。方法选择2018年1月—2023年8月北京市昌平区中西医结合医院收治的106例急性脑梗死患者为研究对象,按不同治疗方法将其分为对照组与观察组,各53例。对照组采用阿司匹林治疗,观察组采用化痰通络汤联合阿司匹林治疗。对比两组患者的临床疗效、神经功能、认知功能、不良反应发生情况。结果治疗前,两组美国国立卫生研究院卒中量表评分对比,差异无统计学意义(P>0.05);治疗后,两组美国国立卫生研究院卒中量表评分均降低,且观察组低于对照组,差异有统计学意义(P<0.05)。观察组治疗总有效率为96.23%,高于对照组的81.13%,差异有统计学意义(P<0.05)。治疗前,两组蒙特利尔认知评估量表评分对比,差异无统计学意义(P>0.05);治疗后,两组蒙特利尔认知评估量表评分均升高,且观察组高于对照组,差异有统计学意义(P<0.05)。两组不良反应发生率对比,差异无统计学意义(P>0.05)。结论急性脑梗死患者采用化痰通络汤联合阿司匹林治疗的效果显著,可改善患者认知功能及神经功能,不良反应较少。 Objective To explore the effects of Huatan Tongluo Decoction combined with aspirin on cognitive function and nervous function in patients with acute cerebral infarction.Methods A total of 106 patients with acute cerebral infarction treated in Changping District Hospital of Traditional Chinese and Western Medicine from January 2018 to August 2023 were selected as the study objects.According to different treatment methods,they were divided into a control group and an observation group,with 53 cases in each group.The control group was treated with aspirin,the observation group was treated with Huatan Tongluo Decoction combined with aspirin.The clinical efficacy,neurological function,cognitive function and occurrence of adverse reactions were compared between the two groups.Results Before treatment,there was no significant difference in the score of National Institutes of Health Stroke Scale between the two groups(P>0.05).After treatment,the score of the National Institutes of Health Stroke Scale in both groups decreased,and the observation group was lower than the control group,the difference was statistically significant(P<0.05).The total effective rate of the observation group was 96.23%,higher than that of the control group(81.13%),and the difference was statistically significant(P<0.05).Before treatment,there was no significant difference in the scores of the Montreal Cognitive Assessment Scale between the two groups(P>0.05).After treatment,the scores of the Montreal Cognitive Assessment Scale increased in both groups,and the observation group was higher than the control group,the difference was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Huatan Tongluo Decoction combined with aspirin in the treatment of acute cerebral infarction has a remarkable effect,which can improve the cognitive function and nervous function of patients with less adverse reactions.
作者 胡晓晴 谭玲 崔宏建 HU Xiaoqing;TAN Ling;CUI Hongjian(Department of Encephalopathy,Beijing Changping District Hospital of Integrated Traditional Chinese and Western Medicine,Beijing,102208,China)
出处 《反射疗法与康复医学》 2024年第7期18-21,共4页 Reflexology And Rehabilitation Medicine
关键词 急性脑梗死 化痰通络汤 阿司匹林 认知功能 神经功能 Acute cerebral infarction Huatan Tongluo Decoction Aspirin Cognitive function Neural function
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