摘要
目的分析我国成人慢性肾脏病(CKD)的患病率。方法检索中国知网、万方数据库、维普数据库、中国生物医学文献数据库、PubMed、Embase、Cochrane Library,对建库截至2021年2月有关中国成人CKD流行病学研究进行分析。结果最终纳入21项研究,总样本量78927例。中国成人CKD患病率为13.1%,女性患病率高于男性。CKD 1~5期患病率分别为5.2%、3.1%、2.2%、0.2%、0.1%。随着年龄增长,CKD患病率逐渐升高。西南地区CKD患病率最高,西北地区CKD患病率最低。2007—2010年以及2011—2014年CKD患病率为13.8%,2015—2018年CKD患病率为10.3%。蛋白尿、血尿及肾功能下降患病率分别为6.8%、5.6%、2.6%,女性患病率均高于男性。微量白蛋白尿患病率为7.8%,显性白蛋白尿患病率为1.6%。结论中国成人CKD患病率较高,以早期病变为主,女性尤为显著,且存在地区差异。
Objective To analyze the prevalence of chronic kidney disease(CKD)in Chinese adults.Methods The epidemiological studies on CKD in Chinese adults included in China National Knowledge Internet,Wanfang database,VIP database,China Biology Medicine disc,PubMed,Embase,and Cochrane Library from the establishment of databases to February 2021 were retrieved and analyzed.Results 21 studies with a total sample size of 78927 cases were finally included.The prevalence of CKD in Chinese adults was 13.1%,with a higher prevalence in women than in men.The prevalence of CKD stages 1-5 was 5.2%,3.1%,2.2%,0.2%,and 0.1%,respectively.The prevalence of CKD gradually increased with age,and was highest in the southwest and lowest in the northwest.The prevalence of CKD was 13.8%in 2007-2010 and 2011-2014,and 10.3%in 2015-2018.The prevalence of proteinuria,hematuria and decreased renal function was 6.8%,5.6%and 2.6%,respectively,with a higher prevalence in women than in men.The prevalence was 7.8%for microalbuminuria and 1.6%for dominant albuminuria.Conclusion The prevalence of CKD in Chinese adults is high and dominated by early lesions,especially significant in women,an d the prevalence shows regional differences.
作者
白雪莲
张佳宜
项国梁
蔡晓青
BAI Xuelian;ZHANG Jiayi;XIANG Guoliang;CAI Xiaoqing(Discipline Inspection and Supervision Department,Veteran Cadres Department,Education Department,Department of Personnel,Xiyuan Hospital of China Academy of Chinese Medical Sciences,Beijing 100091,China)
出处
《中国医药科学》
2022年第9期49-53,共5页
China Medicine And Pharmacy
