摘要
目的 探讨低位直肠癌患者采用腹腔镜全直肠系膜切除术治疗的临床疗效与安全性。方法 选择2016年1月—2021年11月于该院接受手术治疗的低位直肠癌患者66例,根据随机单双号抽签结果分作观察组(33例,单号)与对照组(33例,双号),对照组采取常规开腹下全直肠系膜切除手术治疗,观察组实施腹腔镜全直肠系膜切除术治疗,对比两组患者临床手术指标及术后恢复指标,测定两组患者治疗前后炎症因子(TNF-α、IL-6、CRP)水平变化,统计两组患者术后并发症总发生率。结果 观察组患者手术用时(125.23±10.14)min、胃肠功能恢复时间(1.75±0.35)d、下床时间(5.25±1.01)d及住院总时间(10.45±1.84)d均明显短于对照组,切口长度(4.31±1.02)cm小于对照组,术中出血量(85.88±10.12)m L少于对照组,差异有统计学意义(t=8.240、22.802、13.418、11.912、45.443、24.826,P<0.05);观察组患者术后炎症水平检测结果均低于对照组,差异有统计学意义(P<0.05);观察组患者术后并发症总发生率低于对照组,差异有统计学意义(P<0.05)。结论 低位直肠癌患者通过采取腹腔镜全直肠系膜切除术治疗具有切口小、出血量少、术后恢复快等优点,同时患者术后并发症发生率低,安全性佳。
Objective To investigate the clinical efficacy and safety of laparoscopic total mesorectal excision in patients with low rectal cancer. Methods From January 2016 to November 2021, 66 patients with low rectal cancer who received surgical treatment in the hospital were selected. According to the results of random odd and even numbers, they were divided into observation group(33 cases, odd number) and control group(33 cases, even number). the control group was treated with routine subabdominou total mesenterectorny, and the observation group was treated with laparoscopic total mesenterectomy. The clinical operation indexes and postoperative recovery indexes of the two groups of patients were compared, the changes in the levels of inflammatory factors(TNF-α, IL-6, CRP) before and after treatment in the two groups of patients were measured, and the total incidence of postoperative complications in the two groups of patients was counted. Results The operation time of the observation group(125.23±10.14)min, gastrointestinal function recovery time(1.75±0.35)d, time to get out of bed(5.25±1.01)d and total hospitalization time(10.45±1.84)d were significantly shorter than those of the control group, the incision length was(4.31±1.02)cm less than that of the control group, and the intraoperative blood loss was(85.88 ±10.12) mL less than that of the control group, the difference was statistically significant(t=8.240, 22.802, 13.418, 11.912, 45.443, 24.826, P<0.05);the detection results of postoperative inflammation levels in the observation group were lower than those in the control group, the difference was statistically significant(P<0.05);the total incidence of postoperative complications in the observation group was lower than that in the control group, the difference was statistically significant(P<0.05). Conclusion Laparoscopic total mesorectal excision for patients with low rectal cancer, the difference was statistically significant has the advantages of small incision, less bleeding, and quick postoperative rec
作者
于兵
YU Bing(Department of General Surgery,Yangzhong Hospital of Traditional Chinese Medicine,Zhenjiang,Jiangsu Province,212000 China)
出处
《世界复合医学》
2022年第3期138-141,145,共5页
World Journal of Complex Medicine
关键词
腹腔镜
全直肠系膜切除术
低位直肠癌
并发症
Laparoscopy
Total mesorectal excision
Low rectal cancer
Complications
