摘要
目的了解我国≥40岁绝经后女性骨质疏松症患病率及其影响因素,为我国骨质疏松症防控工作提供科学依据。方法本研究数据来自2018年中国骨质疏松症流行病学调查,覆盖全国11个省(直辖市)44个县(区),通过问卷调查、体格检查收集调查对象相关变量,并采用双能X线吸收法测量腰椎和股骨近端骨密度。应用复杂抽样加权估计我国≥40岁绝经后女性骨质疏松症患病率及其95%CI并分析其影响因素。结果纳入分析5728人,中国≥40岁绝经后女性骨质疏松症患病率为32.5%(95%CI:30.3%~34.7%)。其中,40~、50~、60~、70~、≥80岁绝经后女性骨质疏松症患病率为16.0%(95%CI:4.5%~27.5%)、18.4%(95%CI:15.9%~20.8%)、37.5%(95%CI:34.5%~40.4%)、52.9%(95%CI:47.5%~58.3%)和68.0%(95%CI:55.9%~80.1%);文盲或小学以下文化程度和家庭人均年收入<10000元人群骨质疏松症患病率较高(P<0.001),分别为47.2%(95%CI:43.0%~51.3%)和40.3%(95%CI:36.9%~43.7%);农村[35.1%(95%CI:32.0%~38.1%)]高于城市(P<0.001);低体重、正常体重、超重、肥胖人群骨质疏松症患病率分别为69.9%(95%CI:59.0%~80.8%)、42.2%(95%CI:38.7%~45.7%)、24.2%(95%CI:21.3%~27.1%)和14.6%(95%CI:11.1%~18.0%)。月经维持年限≤30年和绝经年限≥11年骨质疏松症患病率相对较高(P<0.001),分别为46.1%(95%CI:40.8%~51.3%)和48.2%(95%CI:45.0%~51.3%)。多因素logistic回归分析结果显示,年龄≥60岁、文盲或小学以下文化程度、家庭人均年收入<10000元、低体重、月经维持年限≤30年、绝经年限≥11年绝经后女性骨质疏松症患病风险高。结论我国≥40岁绝经后女性骨质疏松症患病率较高,且在不同社会经济地位组间存在差异,应有效开展重点人群骨质疏松症防控工作。
Objective To understand the prevalence of osteoporosis and related factors in postmenopausal women aged≥40 years in China and provide scientific evidence for osteoporosis prevention and control.Methods Data of this study were from the 2018 China Osteoporosis Epidemiological Survey,covering 44 counties(districts)in 11 provinces in China.Related variables were collected by questionnaire survey and physical measurement,and the BMD of lumbar spine and proximal femur was measured by dual-energy X-ray absorption method.The prevalence of osteoporosis and its 95%CI in postmenopausal women aged≥40 years were estimated with complex sampling weights.Results A total of 5728 postmenopausal women aged≥40 years were included in the analysis and the prevalence of osteoporosis was 32.5%(95%CI:30.3%-34.7%).The prevalence of osteoporosis in postmenopausal women aged 40-49 years,50-59 years,60-69 years,70-79 years,and≥80 years were 16.0%(95%CI:4.5%-27.5%),18.4%(95%CI:15.9%-20.8%),37.5%(95%CI:34.5%-40.4%),52.9%(95%CI:47.5%-58.3%),and 68.0%(95%CI:55.9%-80.1%)respectively.The prevalence of osteoporosis was higher(P<0.001)in those with education level of primary school or below(47.2%,95%CI:43.0%-51.3%)and in those with individual annual income less than 10000 Yuan,(40.3%,95%CI:36.9%-43.7%).The prevalence of osteoporosis was 35.1%in rural areas(95%CI:32.0%-38.1%),which was higher than that in urban areas(P<0.001).The prevalence of osteoporosis in low weight,normal weight,overweight and obese groups were 69.9%(95%CI:59.0%-80.8%),42.2%(95%CI:38.7%-45.7%),24.2%(95%CI:21.3%-27.1%)and 14.6%(95%CI:11.1%-18.0%),respectively.The prevalence of osteoporosis in those with menstrual maintenance years≤30 years and in those with menopause years≥11 years were 46.1%(95%CI:40.8%-51.3%)and 48.2%(95%CI:45.0%-51.3%),respectively.Multivariate logistic analysis showed that age≥60 years,education level of primary school or below,annual household income per capita less than 10000 Yuan,low body weight,menstrual maintenance years≤30 years,menopaus
作者
汤淑女
尹香君
余卫
崔露
李志新
崔丽嘉
王临虹
夏维波
Tang Shu'nyu;Yin Xiangjun;Yu Wei;Cui Lu;Li Zhixin;Cui Lijia;Wang Linhong;Xia Weibo(National Center for Chronic and Non-communicable Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 100050,China;Department of Radiology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100730,China;National Center for Women and Children's Health,Chinese Center for Disease Control and Prevention,Beijing 100081,China;Department of Endocrinology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing 100730,China)
出处
《中华流行病学杂志》
CAS
CSCD
北大核心
2022年第4期509-516,共8页
Chinese Journal of Epidemiology
基金
中央转移支付重大公共卫生项目
中国红十字基金会。
