摘要
背景:富血小板纤维蛋白是第二代血小板浓缩物,近年来广泛应用于口腔医学领域。但目前仍无确凿的证据解释其对促进软硬组织愈合保存的影响。目的:针对当前富血小板纤维蛋白在口腔医学的研究概况做一综述。方法:设计综述的撰写结构,检索中国知网和PubMed数据库2001-2021年相关文献,检索词为“Platelet-rich fibrin,Stomatology”“富血小板纤维蛋白,口腔医学”,部分经典文献延长检索时间限制,分析所得文献的摘要及内容,通过纳入和排除得到相关文献,对53篇符合标准的文献进行综述。结果与结论:尽管有文献证实,富血小板纤维蛋白在口腔疾病中对于软硬组织的修复重建有着良好的效果,但是目前的证据并不能明确解释其相关机制。加之富血小板纤维蛋白的制备方法目前还不尽相同,有着种类繁多的富血小板纤维蛋白衍生物以及不同离心方式,因此仍需要大量实验做进一步研究。
BACKGROUND:Platelet-rich fibrin is a second-generation platelet concentrate that has been applied in many fields of dentistry.However,there is no conclusive evidence to explain its effect on promoting the healing and preservation of soft and hard tissues.OBJECTIVE:To review the current research overview of platelet-rich fibrin in stomatology.METHODS:Relevant literature published from 2001 to 2021 was searched in CNKI and PubMed databases with the search terms of“platelet-rich fibrin,stomatology”in Chinese and English,respectively.The search time limit was extended for some classical literature.The abstracts and contents of the retrieved literature were analyzed,and 53 eligible documents were obtained as per inclusion and exclusion criteria.RESULTS AND CONCLUSION:Although it has been documented that platelet-rich fibrin has a good effect in the repair and reconstruction of soft and hard tissues in oral diseases,the current evidence does not clearly explain the mechanism.In addition,the preparation methods of platelet-rich fibrin are not yet the same and there are a wide variety of platelet-rich fibrin derivatives and different centrifugation methods.Therefore,a large number of experiments are still needed in the future.
作者
陈镜桥
李英
孟茂花
徐星星
王勤英
王欢
陆婧
舒佳玉
董强
Chen Jingqiao;Li Ying;Meng Maohua;Xu Xingxing;Wang Qinying;Wang Huan;Lu Jing;Shu Jiayu;Dong Qiang(Affiliated Stomatological Hospital of Guizhou Medical University,Guiyang 550004,Guizhou Province,China)
出处
《中国组织工程研究》
CAS
北大核心
2023年第3期441-446,共6页
Chinese Journal of Tissue Engineering Research
基金
国家自然科学基金(81860192),项目负责人:董强
贵阳市科技计划项目([2017]3040),项目负责人:董强。
关键词
富血小板纤维蛋白
富血小板浓缩物
口腔种植
口腔医学
生物学特性
综述
platelet-rich fibrin
platelet-rich concentrate
dental implantation
stomatology
biological characteristics
review
