摘要
目的分析探讨急性脑梗塞(ACI)患者体内血清降钙素原(PCT)水平与脑水肿严重程度的相关性。方法将河南信合医院2017年4月至2020年4月收治的100名ACI脑水肿患者作为观察对象,所有的患者均根据患者疾病严重程度的不同分为轻症组、中症组及重症组,分析患者入院后2~7 d的空腹血清PCT水平;另将患者根据治疗结果预后的不同分为治疗显效组及治疗无效组。结果入院监测结果显示,轻症组患者在入院2 d PCT水平为(2.83±0.25)μg/L,入院3 d后的PCT水平为(4.56±0.26)μg/L,入院5 d后的PCT水平为(5.26±0.24)μg/L,入院7 d后的PCT水平为(2.86±0.24)μg/L;中症组患者在入院2 d PCT水平为(6.26±0.24)μg/L,入院3 d后的PCT水平为(9.61±0.27)μg/L,入院5 d后的PCT水平为(11.36±1.58)μg/L,入院7 d后的PCT水平为(5.39±0.24)μg/L;重症组患者在入院2 d PCT水平为(16.68±2.14)μg/L,入院3 d后的PCT水平为(18.59±1.57)μg/L,入院5 d后的PCT水平为(22.19±1.47)μg/L,入院7 d后的PCT水平为(14.59±1.57)μg/L。治疗显效组患者的PCT水平明显更低于治疗无效组,对比差异有统计学意义(P<0.05)。结论ACI患者血清PCT水平升高同ACI患者脑水肿严重程度关系密切,当患者PCT水平上升越高时提示患者脑水肿越严重,同时也能够帮助临床观察患者的治疗预后情况,临床可根据患者疾病发作后的PCT水平升高程度对患者脑水肿的严重程度进行评估,及时对患者采取更合理的治疗方案。
Objective To analyze the correlation between serum procalcitonin(PCT)level and the severity of cerebral edema in patients with acute cerebral infarction(ACI).Methods A total of 100 patients with ACI and cerebral edema admitted to in Henan Xinhe Hospital from April 2017 to April 2020 were selected as the object of observation,all patients were divided into mild group,moderate group and severe group according to the severity of disease.The fasting serum PCT level was analyzed 2 to 7 days after admission,in addition,the patients were divided into the effective group and the ineffective group according to the difference of prognosis.Results The results of inpatient monitoring showed that,In the mild group,the level of PCT was(2.83±0.25)μg/L at 2 days after admission,(4.56±0.26)μg/L at 3 days after admission and(5.26±0.24)μg/L at 5 days after admission,the level of PCT was(2.86±0.24)μg/L 7 days after admission.In the moderate group,(6.26±0.24)μg/L 2 days after admission,(9.61±0.27)μg/L 3 days after admission and(11.36±1.58)μg/L 5 days after admission,the level of PCT was(5.39±0.24)μg/L 7 days after admission.In the severe group,(16.68±2.14)μg/L 2 days after admission,(18.59±1.57)μg/L 3 days after admission and(22.19±1.47)μg/L 5 days after admission,the PCT level was(14.59±1.57)μg/L 7 days after admission.The level of PCT in the effective group was significantly lower than that in the ineffective group(P<0.05).Conclusion The increase of serum PCT level in patients with ACI is closely related to the severity of brain edema in patients with ACI.The higher the level of PCT,the more severe the brain edema is,the severity of brain edema can be evaluated according to the level of PCT after the onset of the disease,and more reasonable treatment can be taken in time.
作者
陈长立
CHEN Changli(Department of Rehabilitation Medicine,Henan Xinhe Hospital,Xinyang Henan 465200,China)
出处
《临床研究》
2022年第4期9-11,共3页
Clinical Research
关键词
急性脑梗塞
血清降钙素原
脑水肿
acute cerebral infarction
serum procalcitonin
cerebral edema
