摘要
目的探讨对癌性疼痛患者采用针刺+阿片类药物进行治疗后获得的临床效果。方法选取2018年1月1日至2020年12月31日山东省枣庄市中医医院收治的70例癌性疼痛患者进行治疗研究,将其随机分为西医治疗组(盐酸羟考酮缓释片)和中西医治疗组[针刺+盐酸羟考酮缓释片(阿片类药物)],每组各35例;比较两组患者治疗效果。结果中西医治疗组治疗总缓解率为97.14%,高于西医治疗组的80.00%,差异有统计学意义(P<0.05);治疗前,两组QOL评分比较,差异无统计学意义(P>0.05);治疗后,中西医治疗组QOL评分高于西医治疗组,差异有统计学意义(P<0.05);治疗前,两组KPS评分比较,差异无统计学意义(P>0.05);治疗后,中西医治疗组KPS评分高于西医治疗组,差异有统计学意义(P<0.05);中西医治疗组不良反应(头晕、恶心呕吐、便秘、尿潴留)总发生率为17.14%,明显低于西医治疗组的42.86%,差异有统计学意义(P<0.05);治疗前,两组每24小时阿片类药物用量比较,差异无统计学意义(P>0.05);治疗后,中西医治疗组每24小时阿片类药物用量低于西医治疗组,差异有统计学意义(P<0.05)。结论针刺+阿片类药物应用后,观察疾病缓解率、QOL评分、KPS量表评分、不良反应、每24小时阿片类药物用量,均获得明显改善,可促进癌性疼痛患者预后能力提升。
Objective To explore the clinical effect of acupuncture combined with opioids for patients with cancer pain.Methods A total of 70 patients with cancer pain admitted to our hospital from January 1,2018 to December 31,2020 were selected.They were randomly divided into the western medicine treatment group(oxycodone hydrochloride sustained-release tablets)and the integrative Chinese and western medicine treatment group(acupuncture combined with oxycodone hydrochloride sustained-release tablets[opioids]),with 35 patients in each group.The treatment outcome was compared between the two groups.Results The total remission rate in the integrative Chinese and western medicine treatment group was 97.14%,which was higher than that of 80.00%in the western medicine treatment group,with significant difference(P<0.05).Before treatment,there was no significant difference in the QOL score between the integrative Chinese and western medicine treatment group and the western medicine treatment group(P>0.05).After treatment,the QOL score in the integrative Chinese and western medicine treatment group was higher than that in the western medicine treatment group,with significant difference(P<0.05).Before treatment,there was no significant difference in the KPS score between the integrative Chinese and western medicine treatment group and the western medicine treatment group(P>0.05).After treatment,the KPS score in the integrative Chinese and western medicine treatment group was higher than that in the western medicine treatment group,with significant difference(P<0.05).The total incidence of adverse events(dizziness,nausea,vomiting,constipation,and urinary retention)in the integrative Chinese and western medicine treatment group was 17.14%,which was lower than that of 42.86%in the western medicine treatment group,with significant difference(P<0.05).Before treatment,there was no significant difference in the dosage of opioids per 24 h between the integrative Chinese and western medicine treatment group and the western medicine treatment
作者
郭兴彩
GUO Xingcai(Department of Pain,Zaozhuang Hospital of Traditional Chinese Medicine in Shandong Province,Zaozhuang 277000,China)
出处
《中国现代医生》
2022年第7期120-122,177,共4页
China Modern Doctor
关键词
癌性疼痛
针刺
阿片类药物
盐酸羟考酮缓释片
治疗效果
Cancer pain
Acupuncture
Opioids
Oxycodone hydrochloride sustained-release tablets
Therapeutic effect
