摘要
随着人们对神经系统自身免疫相关疾病的认识和发展,其诊断与治疗水平显著提高,但仍有一些神经系统自身免疫性疾病的病因未明,越来越多研究提出肠道微生物与神经系统免疫性疾病存在密切联系,对菌群的研究将有助于探索发病机制,及早预防疾病进展。
With people′s understanding and development of autoimmune-related diseases of the nervous system,the level of diagnosis and treatment has improved significantly.However,the etiology of some autoimmune diseases of the nervous system is still unknown.There is a close relationship between gut microbiota and nervous system immunity.The research and discussion on the flora will help clarify the pathogenesis and prevent the progress of diseases in the field of preventive medicine.This article summarizes the latest research progress in order to provide new ideas.
作者
赵丽
王佳伟
Zhao Li;Wang Jiawei(Department of Neurology,Beijing Tongren Hospital,Capital Medical University,Beijing 100730,China;Medical Research Center,Beijing Tongren Hospital,Capital Medical University,Beijing 100730,China)
出处
《中华预防医学杂志》
CAS
CSCD
北大核心
2022年第3期256-261,共6页
Chinese Journal of Preventive Medicine
基金
国家自然科学基金(81771313)
国家自然科学基金青年科学基金(81301029)
北京市自然科学基金(7192040)
北京市医院管理局“青苗”计划专项经费(QML20150206)北京市科技计划课题“首都特色”项目(Z171100001017039)
首都卫生发展科研专项(2020-2-2056)。
关键词
脑肠轴
自身免疫疾病
肠道微生物
短链脂肪酸
Gut-brain axis
Autoimmunity disease
Intestinal flora
Short-chain fatty acids
