摘要
目的分析早期胃癌(EGC)患者应用消化内镜黏膜下剥离术(ESD)的肿瘤切除效果和安全性。方法选取2018年2月至2021年2月禹州市中心医院收治的82例EGC患者的临床资料,按随机数字表法分为对照组与研究组,每组41例。对照组予以内镜下黏膜切除术(EMR),研究组予以ESD。比较两组手术临床指标(手术时间、术中出血量、住院时间)、肿瘤切除情况(一次性完全切除、治愈性切除、可能治愈性切除、非治愈性切除、肿瘤复发)及并发症发生情况。结果研究组住院时间短于对照组,术中出血量少于对照组,差异有统计学意义(P<0.05)。研究组一次性完全切除率为82.93%(34/41),治愈性切除率为78.05%(32/41),高于对照组[48.78%(20/41)、39.02%(16/14)],可能治愈性切除率为12.20%(5/41),非治愈性切除率为7.32%(3/41),低于对照组[34.15%(14/41)、24.39%(10/41)],差异有统计学意义(P<0.05)。肿瘤复发率为0.00%(0/41),与对照组[9.76%(4/41)]比较,差异未见统计学意义(P>0.05)。研究组术中出血发生率为4.88%(2/41),低于对照组[19.51%(8/41)],差异有统计学意义(P<0.05)。结论ESD治疗EGC患者可减少术中出血量,提高病灶切除效果,降低并发症发生风险,缩短患者住院时间,并可预防复发,改善预后。
Objective To analyze the effect and safety of endoscopic submucosal dissection(ESD)in patients with early gastric cancer(EGC).Methods Eighty-two patients with EGC in Yuzhou Central Hospital from February 2018 to February 2021 were randomly divided into study group and control group,with 41 cases in each group.The control group was treated with endoscopic mucosal resection(EMR)and the study group was treated with ESD.The clinical indexes(operation time,intraoperative bleeding,hospital stay),tumor resection(one-time complete resection,curative resection,possible curative resection,non curative resection and tumor recurrence)and complications were compared between the two groups.Results The hospital stay in the study group was shorter than that in the control group,and the amount of intraoperative bleeding was less than that in the control group(P<0.05).The one-time complete resection rate was 82.93%(34/41),the curative resection rate was 78.05%(32/41),which was higher than that[48.78%(20/41)and 39.02%(16/14)]in the control group,the possible curative resection rate was 12.20%(5/41),and the non curative resection rate was 7.32%(3/41),which was lower than that[34.15%(14/41)and 24.39%(10/41)]in the control group(P<0.05).The tumor recurrence rate was 0.00%(0/41),and there was no significant difference compared with the control group[9.76%(4/41)](P>0.05).The incidence of intraoperative bleeding in the study group was 4.88%(2/41),which was lower than that in the control group[19.51%(8/41)],and the difference was significant(P<0.05).Conclusions ESD in the treatment of EGC patients can reduce the amount of intraoperative bleeding,improve the effect of lesion resection,reduce the risk of complications,shorten the hospital stay,prevent recurrence and improve the prognosis.
作者
苏红鸽
Su Hongge(Department of Endoscopy Room,Yuzhou Central Hospital,Yuzhou 461670,China)
出处
《临床医学》
CAS
2022年第2期27-29,共3页
Clinical Medicine
关键词
早期胃癌
内镜黏膜下剥离术
内镜下黏膜切除术
肿瘤切除
Early gastric cancer
Endoscopic submucosal dissection
Endoscopic mucosal resection
Tumor resection
