摘要
目的探讨高清白光内镜、色素染色内镜和电子染色内镜对于炎症性肠病患者肠道黏膜异型增生和瘤样病变的检出效果。方法检索PubMed、Web of Science、Cochrane library、Embase、CNKI、万方、维普等数据库中的相关研究,检索时间设定为2010年1月至2021年1月,查找所有长时间患病的炎症性肠病(IBD)患者的内镜筛查临床试验,严格按照纳入与排除标准进行筛选、数据提取和质量评估。并用STATA16版本软件进行meta分析。结果此研究纳入文献数量为10篇,包含1624例患者。meta分析结果显示,色素染色内镜在异型增生病变检出率方面优于高清白光内镜(OR=2.01,95%CI:1.21~3.34,P<0.05),电子染色内镜与色素染色内镜相比无明显优势。结论色素染色内镜可考虑用于炎症性肠病患者的长期病变监测,电子染色内镜的有效性还有待进一步证实,仍需更多的随机对照研究。
Objective To investigate the effects of high-definition white light endoscopy,pigment staining endoscopy and electronic staining endoscopy on the detection of intestinal mucosal dysplasia and tumor-like lesions in patients with inflammatory bowel disease.Methods Related studies were searched in PubMed,Web of Science,Cochrane library,Embase,CNKI,Wanfang,CQVIP and other databases.The search time was from January 2010 to January 2021.All clinical trials of endoscopic screening for patients with chronic IBD were searched.Screening,data extraction and quality assessment were conducted strictly in accordance with the inclusion and exclusion criteria.Stata16 software was used for meta-analysis.Results This study included 10 articles with 1624 patients.Meta-analysis showed that pigment staining endoscopy was superior to high-definition white light endoscopy in detection rate of dysplasia lesions(OR=2.01,95%CI:1.21-3.34,P<0.05),and electronic staining endoscopy had no significant advantages compared with pigment staining endoscopy.Conclusion Pigment staining endoscopy can be considered for long-term lesion monitoring in patients with inflammatory bowel disease.The effectiveness of electronic staining endoscopy needs further investigation,and more randomized controlled studies are still needed.
作者
曹涵钰
CAO Hanyu(Department of Hematology,First Affiliated Hospital of Soochow University,Suzhou 215006,China)
出处
《中国现代医生》
2022年第6期92-98,103,共8页
China Modern Doctor
关键词
炎症性肠病
染色内镜
高清白光内镜
META分析
Inflammatory bowel disease
Staining endoscopy
High-definition white light endoscopy
Meta-analysis
