摘要
目的探讨尼卡地平联合维生素E、钙剂治疗妊娠期高血压的效果及对妊娠结局的影响。方法300例妊娠期高血压患者随机分为两组,对照组采用常规治疗,观察组采用尼卡地平联合维生素E、钙剂治疗,比较两组的血压、凝血指标以及妊娠结局。结果治疗后,观察组的SBP、DBP、FIB水平均低于对照组,APTT、PT均长于对照组,不良妊娠结局发生率低于对照组(P<0.05)。结论尼卡地平联合维生素E、钙剂治疗妊娠期高血压可降低患者血压,调节机体高凝状态,减少不良妊娠结局。
Objective To explore the effect of nicardipine combined with vitamin E and calcium agent in the treatment of gestational hypertension and its impact on pregnancy outcome.Methods 300 cases of patients with gestational hypertension were randomly divided into two groups.The control group received routine treatment,while the observation group was treated with nicardipine combined with vitamin E and calcium agent.The blood pressures,coagulation indicators and pregnancy outcomes were compared between the two groups.Results After treatment,the levels of SBP,DBP and FIB in the observation group were lower than those in the control group,APTT and PT were longer than those in the control group,and the incidence of adverse pregnancy outcomes was lower than that in the control group(P<0.05).Conclusions Nicardipine combined with vitamin E and calcium agent in the treatment of gestational hypertension can lower patients'blood pressure,regulate hypercoagulable state of the body,and reduce adverse pregnancy outcomes.
作者
陈霞
王卫丽
魏培伟
CHEN Xia;WANG Weili;WEI Peiwei(Department of Obstetrics and Gynecology,Huaxian Maternal and Child Health Hospital,Anyang 456408,China)
出处
《临床医学工程》
2022年第4期519-520,共2页
Clinical Medicine & Engineering
关键词
尼卡地平
维生素E
钙剂
妊娠期高血压
妊娠结局
Nicardipine
Vitamin E
Calcium agent
Gestational hypertension
Pregnancy outcome
