摘要
为了深入研究“太白七药”抗肿瘤活性以及为后期临床研究提供新思路,现利用CNKI、PubMed等数据库,对“太白七药”中具有抗肿瘤作用的药物以及发挥其作用的相关机制的研究进展进行综述,并阐述了其活性部位和成分的抗肿瘤通路及靶点,提出了“太白七药”抗肿瘤研究过程中存在的如机制单一、有效成分不明确等问题。
In order to study the antitumor activity of Taibai Qi medicines and to provide new ideas for later clinical research,the research progress of the drugs with antitumor effects and the related mechanisms of their effects in Taibai Qi medicines is reviewed using CNKI and PubMed databases.The research progress of anti-tumor drugs and the related mechanisms of their effects are reviewed,and the anti-tumor pathways and targets of their active sites and components are described,and the problems such as single mechanism and unclear active ingredients in the anti-tumor research of Taibai Qi medicines are proposed.
作者
李鑫
王冯瑞
丁超
姜祎
张化为
李玉泽
宋小妹
张东东
王薇
Li Xin;Wang Fengrui;Ding Chao;Jiang Yi;Zhang Huawei;Li Yuze;Song Xiaomei;Zhang Dongdong;Wang Wei(Shaanxi University of Chinese Medicine,College of Pharmacy,Xianyang 712046,China)
出处
《中国野生植物资源》
CSCD
2022年第2期38-48,57,共12页
Chinese Wild Plant Resources
基金
陕西省科技厅自然科学基础研究计划项目(2021JQ-744)
陕西省重点研发计划项目(2019ZDLSF04-03-02)
陕西中医药大学学科创新团队项目(2019-YL12)。
关键词
太白七药
抗肿瘤活性
作用机制
活性成分
Taibai Qi medicines
Antitumor activity
Mechanism
Active constituents