摘要
人参(Panax ginseng)作为一种具有良好药理活性的药用植物,一直受到广泛关注,而其能够发挥药理活性的部分主要是人参皂苷,主要包括齐墩果烷型和达玛烷型。据研究表明,人参皂苷下游生物合成途径最后一步离不开糖基转移酶的催化过程。因其主要以UDP-糖作为供体分子,所以称之为UDP-糖基转移酶,即UGT。本文结合前人的大量研究对糖基转移酶包括UGT及UGT的功能进行概述,同时介绍了人参UGT基因家族功能到目前为止的研究进展。可为后续对UGT基因家族的研究提供借鉴。
Ginseng(Panax ginseng),as a medicinal plant with good pharmacological activity,has been widely concerned,and ginsenosides are the main pharmacological activities of ginsenosides,including oleanane type and damarane type.The studies have shown that the last step of the downstream biosynthesis pathway of ginsenosides can't be separated from the glycosylation process catalyzed by glycosyltransferase.Because it mainly uses UDP-sugar as the donor molecule,it is called UDP-glycosyltransferase,or UGT.Combined with a large number of previous studies,this paper summarizes the functions of glycosyltransferases including UGT and UGT,and introduces the research progress of the function of ginseng UGT gene family so far.It can be used as a reference for the follow-up study of UGT gene family.
作者
王海娇
李宇兴
佟爱仔
刘伟
胡勇军
WANG Hai-jiao;LI Yu-xing;TONG Ai-zi;LIU Wei;HU Yong-jun(Changchun Normal University,Changchun 130032;Tonghua Normal University,Tonghua 134002)
出处
《人参研究》
2022年第2期54-57,共4页
Ginseng Research
