摘要
目的:观察健脾生血颗粒联合琥珀酸亚铁片治疗儿童缺铁性贫血的临床疗效。方法:选取100例缺铁性贫血患儿作为研究对象,按随机数字表法分为试验组及对照组各50例。对照组给予琥珀酸亚铁片,试验组在对照组基础上给予健脾生血颗粒,2组均治疗4周。比较2组临床疗效,比较2组治疗前后中医证候评分、生长发育[精神运动发育指数(PDI)、智力发育指数(MDI)、发育商(DQ)]及血清学指标[血清铁蛋白(SF)、平均红细胞血红蛋白(MCH)、血红蛋白(Hb)]水平变化。结果:试验组临床疗效总有效率为92.00%,高于对照组76.00%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组面色、舌唇色、神疲乏力、食欲中医证候评分及总分均较治疗前降低,试验组上述4项中医证候评分及总分均低于对照组,差异均有统计学意义(P<0.05)。治疗后,2组PDI、MDI、DQ评分均较治疗前升高,试验组上述3项评分均高于对照组,差异均有统计学意义(P<0.05)。治疗后,2组血清SF、Hb、MCH水平均较治疗前升高,试验组上述3项水平均高于对照组,差异均有统计学意义(P<0.05)。结论:健脾生血颗粒联合琥珀酸亚铁片可缓解缺铁性贫血患儿的贫血症状,促进患儿生长发育。
Objective:To observe the clinical effect of Jianpi Shengxue granules combined with ferrous succinate tablets for children with iron deficient anemia.Methods:A total of 100 cases of children with iron deficient anemia were selected and divided into the control group and the experiment group according to the random number table method,with 50 cases in each group.The control group was given ferrous succinate tablets and the experiment group was treated with Jianpi Shengxue granules combined with ferrous succinate tablets.Both groups were treated for four weeks.Clinical effects were compared between the two groups.Before and after treatment,changes in Chinese medicine syndrome scores,growth and development[Psychomotor Developmental Index(PDI),Mental Development Index(MDI),developmental quotient(DQ)in psychomotor development],and serology indexes[serum ferritin(SF),mean corpuscular hemoglobin(MCH),hemoglobin(HB)]were compared between the two groups.Results:The total effective rate was 92.00%in the experiment group,higher than that of 76.00%in the control group,the difference being significant(P<0.05).After treatment,the scores of facial complexion,tongue and lip color,lassitude of spirit and lack of strength,and appetite as well as the total scores in the two groups were decreased when compared with those before treatment,and the above four scores and the total score in the experiment group were lower than those in the control group,differences being significant(P<0.05).After treatment,scores of PDI,MDI and DQ in the two groups were increased when compared with those before treatment,and the above three scores in the experiment group were higher than those in the control group,differences being significant(P<0.05).After treatment,levels of SF,Hb,and MCH in serum in the two groups were increased when compared with those before treatment,and the above three levels in the experiment group were higher than those in the control group,differences being significant(P<0.05).Conclusion:Jianpi Shengxue granules combined with fe
作者
傅跃燕
陈芳
丁传彪
FU Yueyan;CHEN Fang;DING Chuanbiao
出处
《新中医》
CAS
2022年第5期148-151,共4页
New Chinese Medicine
关键词
缺铁性贫血
儿童
健脾生血颗粒
琥珀酸亚铁片
生长发育
Iron deficient anemia
Children
Jianpi Shengxue granules
Ferrous succinate tablets
Growth and development
