摘要
塑料工业的发展在给人类社会带来方便的同时,也导致大量的废旧塑料垃圾不断产生,给全球生态系统带来了严重的负担。我国是塑料生产和消费大国,在塑料的研究和治理等方面都面临空前的国际舆论压力,近年来,我国相继推出一系列限塑禁塑政策,发展高效塑料降解策略已成为生态、环境、能源等领域发展的迫切需求。聚对苯二甲酸乙二醇酯(PET)是应用最广泛的合成聚酯之一,通过生物酶法对其回收是一种绿色理想的处理方法,为解决PET废弃污染提供新契机。近年来,不同来源的PET水解酶可分为来自嗜热微生物(放线菌和真菌)的嗜热降解酶和来自中温细菌的温和降解酶。这2种在不同温度下发挥高效PET降解能力的酶对于PET废弃塑料处理有着不同的优势。本文主要对可回收PET废物以及无法有效回收的微塑料的生物降解的研究现状进行梳理总结,重点阐述了PET降解酶设计改造策略和应用前景,以期为开发高效PET降解酶提供参考依据,为资源可持续发展和环境治理等重大问题提供资源储备。
With the development of plastic industry, human society has been facilitated a lot. Meanwhile, a large number of plastic wastes are constantly produced, causing a serious burden on the global ecosystem.As a major producer and consumer of plastics, China is facing unprecedented international public pressure in terms of research and governance of plastics.In recent years, China has launched a series of plastic restriction and prohibition policies.There is an urgent need to develop environmentally friendly and efficient methods for degrading plastic wastes.Polyethylene terephthalate(PET) is one of the most widely used synthetic polyesters.Enzymatic hydrolysis of PET may provide a green and ideal means of solving PET waste pollution.In recent years, a dozen PET hydrolases have been identified that can be classified into thermophilic degrading enzymes derived from thermophilic microorganisms(actinomycetes and fungi) and mesophilic degrading enzymes from mesophilic bacteria.In this review we summarize the current researches on the biodegradation and conversion of PET waste and microplastics, mainly focusing on PET hydrolase redesign strategies and their applications.We aimed to provide a theoretical basis for the engineering of more efficient PET hydrolases and to reserve a resource to solve major issues, such as sustainable resource development and environmental management.
作者
刘欣悦
崔颖璐
LIU Xinyue;CUI Yinglu(CAS Key Laboratory of Microbial Physiological and Metabolic Engineering,State Key Laboratory of Microbial Resources,Institute of Microbiology,Chinese Academy of Sciences,Beijing 100101,China;School of Life Sciences,University of Science and Technology of China,Hefei 230026,China)
出处
《生物加工过程》
CAS
2022年第2期226-234,共9页
Chinese Journal of Bioprocess Engineering
基金
国家重点研发计划(2018YFA0901600)
国家自然科学基金面上项目(31870055、32170033)
中国科学院生物资源衍生库项目(KFJBRP-009-002)
中国科学院战略生物资源能力建设项目(KFJ-BRP-017-58)。
关键词
聚对苯二甲酸乙二醇酯
PET降解酶
生物降解
设计改造
限塑
生物循环经济
polyethylene terephthalate
polyethylene terephthalate(PET)degrading enzyme
biodegradation
enzyme redesign
plastic restriction
biological circular economy
