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玻璃体切除联合内界膜剥离术治疗高度近视黄斑裂孔的疗效观察

Efficacy of vitrectomy combined with internal limiting membrane peeling in treatment of high myopia and macular hole
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摘要 目的观察高度近视黄斑裂孔采用玻璃体切除与内界膜剥离术治疗的疗效。方法回顾性分析2019年1月-2020年1月我院收治的且在该期间内完成3个月术后随访的60例高度近视黄斑裂孔患者的临床资料,依据治疗方式不同分为对照组(玻璃体切除术治疗,30例)与观察组(玻璃体切除与内界膜剥离术联合治疗,30例)。对比两组患者手术前后最佳矫正视力(Best corrected visual acuity,BCVA)与裂孔闭合率,同时比较两组患者视网膜复位情况。结果术前与术后1周,观察组患者BCVA[(0.14±0.05)LogMAR、(0.17±0.06)LogMAR]与对照组患者[(0.13±0.03)LogMAR、(0.16±0.04)LogMAR]相比,差异无统计学意义(t=0.939、0.760,P=0.352、0.451);术后1个月与术后3个月,观察组BCVA[(0.23±0.07)LogMAR、(0.29±0.03)LogMAR]较对照组患者[(0.19±0.06)LogMAR、(0.25±0.06)LogMAR]高,差异有统计学意义(t=2.376、3.266,P=0.021、0.002);术后3个月,观察组患者裂孔闭合率(86.67%)较对照组患者(53.33%)均较高,差异有统计学意义(χ^(2)=7.937,P=0.005);观察组患者视网膜复位率(93.33%)较对照组患者(86.67%)略高,但组间对比,差异无统计学意义(χ^(2)=0.185,P=0.389)。结论高度近视黄斑裂孔采用玻璃体切除与内界膜剥离术联合治疗患者有助于提高BCVA,促进裂孔闭合与视网膜复位,值得在临床应用。 Objective To investigate the clinical effects of vitrectomy combined with internal limiting membrane peeling in treatment of high myopia and macular hole.Methods The clinical data of 60 patients with high myopia and macular hole who treated in the hospital from January 2019 to January 2020 and completed 6 months of postoperative follow-up within this period were retrospectively analyzed.The patients were divided into control group(vitrectomy,30 cases)and observation group(vitrectomy combined with internal limiting membrane peeling,30 cases)according to treatment methods.The best corrected visual acuity(BCVA)and hole closure rate were compared of the two group’s patients before and after surgery,and retinal reattachment were compared between two groups.Results Before operation and 1 week after operation,compared the BCVA[(0.14±0.05)LogMAR,(0.17±0.06)LogMAR]of the observation group with the control group[(0.13±0.03)LogMAR,(0.16±0.04)LogMAR],the difference was not statistically significant(t=0.939,0.760,P=0.352,0.451);1 month after operation and 3 months after operation,the BCVA[(0.23±0.07)LogMAR,(0.29±0.03)LogMAR]of patients in the observation group was higher than that of the control group[(0.19±0.06)LogMAR,(0.25±0.06)LogMAR],the difference was statistically significant(t=2.376,3.266,P=0.021,0.002);3 months after operation,the hole closure rate of the observation group(86.67%)was higher than that of the control group(53.33%),and the difference was statistically significant(χ^(2)=7.937,P=0.005);the retinal reattachment rate of the observation group(93.33%)was slightly higher than that of the control group(86.67%),but the difference between the groups was not statistically significant(χ^(2)=0.185,P=0.389).Conclusion Vitrectomy combined with internal limiting membrane peeling in treatment of high myopia and macular hole has significant clinical effects,it can increase BCVA of patients,promote the closure of the hole and reattachment of the retina,which is worthy of clinical application.
作者 付政 王瑞峰 徐一帆 唐文建 FU Zheng;WANG Rui-feng;XU Yi-fan(Department of the fist district of fundus diseases,Zhenghou second pople's Hospial,Zhenghou,450000)
出处 《实用防盲技术》 2022年第1期17-19,F0002,共4页 Journal of Practical Preventing Blind
关键词 高度近视 黄斑裂孔 玻璃体切除 内界膜剥离术 最佳矫正视力 裂孔闭合率 视网膜复位 High myopia Macular hole Vitrectomy Internal limiting membrane peeling Best corrected visual acuity Hole closure rate Retinal reattachment
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