摘要
目的探究股骨头坏死松质骨微观结构参数和力学性能的空间分布规律,为临床诊断中科学评估病灶对病情的影响提供理论依据。方法结合影像学测量和数值模拟方法,定量分析不同区域松质骨的微观结构参数和力学性能,分别从冠状面、矢状面和水平面投影方向上探究松质骨生物力学特征的空间分布特点。结果在股骨头冠状面和矢状面投影方向上,松质骨的微观结构特征与力学性能大致呈Y型分布,Y形区域内松质骨的力学性能高于其他区域,该分布特点与股骨头内的主压应力束的位置相吻合。结论位于股骨头Y形区域内的坏死灶对股骨头内应力分布的影响程度会更大,更有可能导致病情恶化。临床诊断中应充分考虑坏死灶和Y形区域的位置关系。
Objective To explore the spatial distribution of microstructural parameters and mechanical properties for trabecular bone in the femoral head with osteonecrosis.Methods Microstructural parameters and mechanical properties of trabecular bone in different regions were analyzed by combined use of imaging measurements and numerical simulation method,and the spatial distribution of biomechanical properties for trabecular bone along coronal,sagittal and vertical directions was investigated.Results Microstructural characteristics and mechanical properties of trabecular bone were Y-shaped distributed along coronal and sagittal directions,and mechanical properties of trabecular bone in Y-shaped region were higher than those in the other regions.Such distribution characteristics was consistent with the location of principle compressive group in the femoral head.Conclusions Necrotic lesions in Y-shaped region had a greater influence on stress distribution of the femoral head and might cause the deterioration of osteonecrosis.The spacial correlation between necrotic lesions and Y-shaped region should be fully considered during clinical diagnosis.
作者
冯成龙
杨贤达
冯文韬
王丽珍
樊瑜波
FENG Chenglong;YANG Xianda;FENG Wentao;WANG Lizhen;FAN Yubo(Beijing Advanced Innovation Centre for Biomedical Engineering,Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education,School of Biological Science and Medical Engineering;School of Engineering Medicine,Beihang University,Beijing 100083,China)
出处
《医用生物力学》
CAS
CSCD
北大核心
2022年第1期27-32,共6页
Journal of Medical Biomechanics
基金
国家自然科学基金项目(11822201)。
关键词
股骨头坏死
松质骨
微观结构参数
力学性能
空间分布
osteonecrosis of the femoral head(ONFH)
trabecular bone
microstructural parameters
mechanical properties
spatial distribution
