摘要
针对疝修补合成补片植入后带来的多种并发症问题,明确了并发症的诱发因素为病原菌带来的污染和补片本体材料导致的异物反应。以临床常用的经编补片为研究对象,将目前应对疝修补术后并发症的手段分为经编结构调控和表面修饰改性。根据应对场景(有菌性炎症和无菌性炎症)和使用场合(腹腔内和腹腔外)的不同,对表面修饰改性进行了分类阐述。列举了近年来相关研究及临床商用补片取得的成果进展,并将表面改性补片归纳为抗菌型、防粘连型、抗炎型,通过分别概述其相应的作用机制及并发症应对效果,分析了当前3种不同类型表面改性补片存在的问题,并指出具有高附加功能的经编补片将是未来的发展方向。
In view of the multiple complications caused by synthetic meshes implanted for hernia repair,a literature review was carried out and it revealed that the triggering factors of complications are the pollution from the pathogenic bacteria and the foreign body reaction from the mesh.Regarding the commonly used warp-knitted mesh,the present treatments were divided into the warp-knitted structure adjustment and the surface modification.According to the different scenarios(bacterial or aseptic inflammation)and occasions(intraperitoneal or extraperitoneal),the surface modifications were classified and explained.The progress in related researches and clinical commercial meshes in recent years were scrutinized,and summarized three types of modified meshes(anti-bacterial,anti-adhesion,anti-inflammation)were summarised.By outlining the corresponding mechanisms and effects on complications,this paper pointed out the current problems of these types of modified meshes and concluded that the high-value warp-knitted mesh is the future development direction.
作者
乔燕莎
毛迎
徐丹瑶
李彦
李绍杰
王璐
唐健雄
QIAO Yansha;MAO Ying;XU Danyao;LI Yan;LI Shaojie;WANG Lu;TANG Jianxiong(College of Textiles, Donghua University, Shanghai 201620, China;Key Laboratory of Textile Science & Technology, Ministry of Education, Donghua University, Shanghai 201620, China;Hernia and Abdominal Wall Surgery Center, Department of General Surgery, Huadong Hospital of Fudan University, Shanghai 200040, China)
出处
《纺织学报》
EI
CAS
CSCD
北大核心
2022年第3期1-7,共7页
Journal of Textile Research
基金
高等学校学科创新引智计划2.0项目(BP0719035)。
关键词
疝补片
医用纺织品
经编补片
疝修补
并发症
结构调控
表面修饰
hernia mesh
medical textiles
warp-knitted mesh
hernia repair
complications
structure adjustment
surface modification
