摘要
目的:探讨腹腔镜子宫切除术对患者围术期卵巢血流指标及氧化损伤的影响。方法:选取2019年3月-2021年3月庄河市中心医院收治的需行子宫切除术的患者136例,根据手术方式不同将其分为研究组(腹腔镜子宫切除术,68例)和对照组(经腹子宫切除术,68例)。比较两组患者手术前后舒张末期最小血流速度(Vmin)、收缩期最大血流速度(Vmax)、搏动指数(PI)、阻力指数(RI)、血清肌红蛋白(Myo)、缺血修饰白蛋白(IMA)、总抗氧化能力(TAC)、卵泡刺激素(FSH)、雌激素(E_(2))水平变化以及手术相关指标情况。结果:术后2 d,两组患者Vmin、Vmax、PI、RI均低于术前,且研究组Vmin、Vmax、PI水平均高于对照组,RI水平低于对照组,差异均有统计学意义(P<0.05)。术后24 h,两组患者血清Myo、IMA均高于术前,TAC水平均低于术前,且研究组血清Myo、IMA水平均低于对照组,TAC水平高于对照组,差异均有统计学意义(P<0.05)。两组患者术后30 d FSH水平均高于术前,E_(2)水平均低于术前,其中研究组患者术后30 d FSH水平低于对照组,E_(2)水平高于对照组,差异均有统计学意义(P<0.05)。研究组患者的手术时间长于对照组,术中出血量少于对照组,住院时间短于对照组,差异均有统计学意义(P<0.05)。结论:腹腔镜子宫切除术对患者围术期卵巢血流、功能及氧化损伤影响程度较低,术中出血量相对较少,利于患者术后恢复。
Objective:To investigate the effect of laparoscopic hysterectomy on ovarian blood flow indexes and oxidative damage during perioperative period.Method:A total of 136 patients who underwent hysterectomy in Zhuanghe Central Hospital from March 2019 to March 2021 were selected,they were divided into study group(laparoscopic hysterectomy,68 cases)and control group(abdominal hysterectomy,68 cases)according to different surgical methods.End-diastolic minimal blood flow velocity(Vmin),the largest systolic blood flow velocity(Vmax),pulse index(PI),resistance index(RI),serum myoglobin(Myo),ischemia modified albumin(IMA),total antioxidant capacity(TAC),follicle-stimulating hormone(FSH),estrogen(E_(2))level changes before and after surgery and the operation related indicators were compared between the two groups.Result:2 d after surgery,Vmin,Vmax,PI and RI in two groups were lower than those before surgery,and Vmin,Vmax and PI levels in study group were higher than those in control group,RI level was lower than that of the control group,the differences were statistically significant(P<0.05).24 h after surgery,serum Myo and IMA in two groups were higher than those before surgery,and TAC level was lower than that before surgery,serum Myo and IMA levels in study group were lower than those of control group,and TAC level was higher than that of control group,the differences were statistically significant(P<0.05).30 d after surgery,FSH level in two groups were higher than those before surgery,while E_(2) level were lower than those before surgery,FSH level in study group was lower than that in control group,while E_(2) level was higher than that in control group,the differences were statistically significant(P<0.05).The operative time of patients in the study group was longer than that in the control group,the amount of intraoperative blood loss was less than that in the control group,and the hospital stay was shorter than that in the control group,the differences were statistically significant(P<0.05).Conclusion:Laparoscopic hy
作者
庄雨
ZHUANG Yu(The Central Hospital of Zhuanghe City,Liaoning Province,Zhuanghe 116400,China)
出处
《中国医学创新》
CAS
2022年第5期27-31,共5页
Medical Innovation of China
关键词
腹腔镜子宫切除术
围术期
卵巢血流
氧化损伤
Laparoscopic hysterectomy
Perioperative period
Ovarian blood flow
Oxidative damage
