摘要
目的研究炮制对于中药化学成分以及药理作用的影响。方法本文选择葛根饮片作为研究对象,随机分成两组,观察组为炮制后,对照组为炮制前,分析炮制前后葛根化学成分。结果经本文研究,炮制前Fe 485.41 mg,Cu 7.21 mg,Zn 16.35 mg。炮制后Fe 128.46 mg,Cu 7.68 mg,Zn 15.12 mg。两组对比,Fe含量差异显著(P<0.05),Cu、Zn含量无统计学意义(P>0.05)。水浸液炮制后葛根素(1.70%)和总黄酮(1.91%)含量明显增加,差异显著(P<0.05)。水浸液炮制后颜色(黄棕)和浸出物(18.74%)无明显变化,无统计学意义(P>0.05)。醇浸液炮制后葛根素(2.63%)、浸出物(13.66%)、总黄酮(2.76%)有所降低,差异显著(P<0.05)。醇浸液炮制后颜色(黄棕)无明显差异,无统计学意义(P>0.05)。结论经过炮制后,葛根化学成分出现显著变化,葛根药效显著增强,可取得更好的治疗效果。部分中药经炮制后影响其药效,或改变其性状,给药时需注意炮制方法。在临床应用上经过科学炮制,部分中药药效得到显著增强,毒性得到有效降低,合理炮制有助于改善治疗效果,促进患者康复速度,缓解患者病情。
Objective To study the effect of processing on the chemical components and pharmacological effects of traditional Chinese medicine.Methods Pueraria decoction pieces were selected as the research object and randomly divided into two groups.The observation group was after processing and the control group was before processing.The chemical components of Pueraria before and after processing were analyzed.Results According to the study,Fe 485.41 mg,Cu 7.21 mg and Zn 16.35 mg were prepared before processing.After processing,Fe 128.46 mg,Cu 7.68 mg,and Zn 15.12 mg.There was significant difference in Fe content between the two groups(P<0.05).There was no significant difference in Cu and Zn content(P>0.05).The content of Puerarin(1.70%)and total flavonoids(1.91%)increased significantly after water infusion,and the difference was significant(P<0.05).There was no significant change in color(yellow brown)and extract(18.74%)after water infusion(P>0.05).Puerarin(2.63%),extract(13.66%)and total flavonoids(2.76%)decreased after alcohol extracts,and the difference was significant(P<0.05).There was no significant difference in color(yellow brown)after alcohol extracting,and there was no statistical significance(P>0.05).Conclusion After processing,the chemical composition of kudzuvine root has changed significantly,and the effect of kudzuvine root is significantly enhanced,which can achieve better therapeutic effect.Some Chinese medicines may affect their efficacy after being processed or change their traits.After scientific application in clinical application,the efficacy of some Chinese medicines has been significantly enhanced,the toxicity has been effectively reduced,and reasonable processing can help improve the treatment effect,promote the recovery rate of patients,and alleviate the patient's condition.
作者
高月颖
GAO Yueying(Zhuanghe Central Hospital,Zhuanghe 116400,China)
出处
《中国医药指南》
2022年第7期107-109,共3页
Guide of China Medicine
关键词
中药成分
药理作用
炮制
Traditional Chinese medicine ingredients
Pharmacological effects
Processing
