摘要
目的 探讨H型高血压患者采取马来酸依那普利叶酸片进行治疗的临床效果。方法 100例H型高血压患者,根据入院顺序不同分为对照组与研究组,各50例。对照组患者接受马来酸依那普利片进行治疗,研究组患者接受马来酸依那普利叶酸片进行治疗。对比两组患者心脑血管事件发生情况、治疗效果、血浆同型半胱氨酸水平改善情况及治疗前后血浆同型半胱氨酸水平。结果 研究组患者心脑血管事件发生率4.0%显著低于对照组的50.0%,差异有统计学意义(P<0.05)。两组患者治疗总有效率对比差异无统计学意义(P>0.05)。研究组患者血浆同型半胱氨酸水平改善有效率90.0%显著高于对照组的70.0%,差异有统计学意义(P<0.05)。治疗后,研究组患者血浆同型半胱氨酸水平(11.22±2.33)μmol/L低于对照组的(19.44±4.24)μmol/L,差异有统计学意义(P<0.05)。结论 对H型高血压患者应用马来酸依那普利叶酸片进行治疗的效果明显,能够显著降低患者血压水平以及血浆同型半胱氨酸水平,进一步提高疾病的整体治疗效果,应该给予大力的推广与应用。
Objective To discuss the clinical effect of enalapril maleate folic acid tablet in the treatment of H-type hypertension.Methods A total of 100 patients with H-type hypertension were divided into the control group and the research group according to their order of admission,with 50 cases in each group.Patients in the control group received enalapril maleate tablets for treatment,and patients in the research group received enalapril maleate folic acid tablets for treatment.Both groups were compared in terms of occurrence of cardiocerebrovascular events,therapeutic effect,improvement of plasma homocysteine,and plasma homocysteine level before and after treatment.Results The incidence of cardiocerebrovascular events 4.0%in the research group was significantly lower than 50.0%in the control group,and the difference was statistically significant(P<0.05).There was no statistically significant difference in the total effective of treatment between the two groups(P>0.05).The improvement of plasma homocysteine 90.0%in the research group was significantly higher than 70.0%in the control group,and the difference was statistically significant(P<0.05).After treatment,the plasma homocysteine level(11.22±2.33)μmol/L of the research group was lower than(19.44±4.24)μmol/L of the control group,and the difference was statistically significant(P<0.05).Conclusion Enalapril maleate folic acid tablet has obvious effect on patients with H-type hypertension,which can significantly reduce the blood pressure level and plasma homocysteine level of patients,and further improve the overall therapeutic effect.Therefore,it should be promoted and applied.
作者
侯健
HOU Jian(Central Hospital of Changtu County,Tieling 112599,China)
出处
《中国实用医药》
2022年第5期132-134,共3页
China Practical Medicine
