摘要
背景不合理抗菌药物处方的开具在导致抗菌药物耐药性增强的同时,也严重威胁着公众的健康,而医生抗菌药物使用知识水平、对抗菌药物使用的态度可直接影响其抗菌药物处方开具行为。目的了解2018、2020年湖北省基层医生抗菌药物使用知识水平、对抗菌药物的使用态度,分析其变化特征和原因,并提出针对性的干预措施,以促进基层医生合理使用抗菌药物。方法于2018年4—6月采用两阶段分层整群随机抽样方法,于2019年11月至2020年1月采用两阶段整群随机抽样方法,选取湖北省基层医疗卫生机构中具有抗菌药物处方开具权,并在调查前3个月内开具抗菌药物处方≥100张的医生为研究对象。采用自设问卷对其进行调查,内容包括基层医生基本情况、抗菌药物使用知识〔10种常见场景中是否应该使用(目标)抗菌药物〕、对抗菌药物的使用态度(5种可能影响抗菌药物使用行为的态度)。未进行倾向得分匹配(PSM)前,分析并比较2018、2020年湖北省基层医生抗菌药物使用知识总得分及各条目的正确回答率、抗菌药物使用态度总得分及各条目得分情况。将2020年调查对象作为处理组,将2018年调查对象作为控制组,采用PSM法进行配对后,对湖北省基层医生抗菌药物使用知识和态度总得分的变化特征及原因进行分析。结果2018、2020年分别回收有效问卷637、616份。未进行PSM前,2020年湖北省基层医生抗菌药物使用知识总得分为(5.54±1.46)分,高于2018年的(5.25±1.35)分,差异有统计学意义(P<0.05)。2020年调查对象对头孢曲松透过血脑屏障的效果(48.5%比39.6%)和氨基糖苷类的给药方法(55.7%比44.0%)的正确回答率高于2018年,差异有统计学意义(P<0.05)。2020年湖北省基层医生抗菌药物使用态度总得分为(55.41±5.02)分,高于2018年的(53.29±5.21)分,差异有统计学意义(P<0.05)。2020年调查对象在因满足患者需求�
Background Physicians'irrational antibiotic prescriptions are fueling antibiotic resistance and seriously threatening public health.Physicians'knowledge and attitudes towards antibiotic use will directly affect their behaviors.Objective To describe the status in knowledge and attitudes regarding antibiotic use among primary care physicians in Hubei Province in 2018 and 2020,analyze the changes and relevant reasons over these two years,and to present relevant interventions,promoting rational antibiotic use in primary care physicians.Methods Two surveys were separately conducted(one was conducted from April to June 2018 with a stratified two-stage cluster sample,and the other was conducted from November 2019 to January 2020 with a two-stage cluster random sample)among Hubei's primary care physicians with the qualification of prescribing antibiotics who had written over 100 antibiotic prescriptions within 3 months prior to the survey.A self-developed questionnaire was used in the surveys to acquire information about demographics,knowledge of antibiotic use(whether antibiotics should be used in 10 common situations),and attitudes(5 types of attitudes that may affect antibiotic use behavior).A descriptive analysis was conducted on the accuracy rate and total scores of antibiotic use knowledge as well as total and item scores of attitudes to examine primary care physicians'knowledge and attitudes towards antibiotic use during 2018 and 2020.To determine changes in knowledge and attitudes within two years,propensity score matching(PSM)was used,with participants in 2018 designated as the control group and those in 2020 as the treatment group.Results 637 respondents of the 2018 survey and 616 respondents of the 2020 survey were included for final analysis.Before PSM matching,the mean score of antibiotic use knowledge of the 2020 survey respondents was statistically higher than that of 2018 survey respondents〔(5.54±1.46)vs(5.25±1.35)〕(P<0.05).Moreover,the 2020 survey respondents also had statistically higher accuracy
作者
段立霞
刘晨曦
DUAN Lixia;LIU Chenxi(School of Medicine and Health Management,Tongji Medical College of Huazhong University of Science&Technology,Wuhan 430030,China)
出处
《中国全科医学》
CAS
北大核心
2022年第10期1238-1245,共8页
Chinese General Practice
基金
国家自然科学基金青年科学基金项目(71904053)。
关键词
基层医疗卫生机构
抗菌药物
知识
态度
倾向得分匹配
湖北
Primary healthcare institutions
Antibiotic
Knowledge
Attitude
Propensity score matching
Hubei
