摘要
目的:探讨活血利水法对预防全膝置换术后下肢深静脉血栓的影响。方法:收集2018年9月至2020年1月行全膝关节置换术的患者56例,采用随机数字法分为治疗组和对照组(各28例),其中治疗组术后予活血利水法联合低分子肝素钠进行治疗,对照组术后仅予低分子肝素钠进行治疗。术前及术后均予监测凝血功能、视觉模拟评分(VAS)、下肢周径测量及下肢深静脉B超检查。结果:血浆D-二聚体、纤维蛋白原术后第7天浓度差异有统计学意义(P<0.05)。视觉模拟评分(VAS):治疗组与对照组术前、术后第1天差异均无统计学意义(P>0.05),术后第3天、第7天差异均有统计学意义(P<0.01)。下肢周径值:治疗组与对照组术后大腿周径变化值及小腿周径变化值差异有统计学意义(P<0.01)。下肢深静脉B超:治疗组与对照组均未发现下肢静脉血栓,治疗组改善程度明显优于对照组,差异有统计学意义(P<0.01)。结论:活血利水法能改善全膝关节置换术后血液高凝状态,且能快速减轻全膝关节置换术后疼痛及缓解肢体肿胀。
Objective:To explore the efficacy of traditional Chinese medicine on the prevention of deep vein thrombosis of lower limbs after total knee arthroplasty.Methods:A total of 56 patients who underwent total knee arthroplasty from September 2018 to January 2020 were collected.They were divided into treatment group and control group with 28 cases each by random number method.The treatment group was treated with the method of activating blood and diuresis of traditional Chinese medicine combined with low-molecular-weight heparin sodium after surgery.And the control group was only treated with low-molecular-weight heparin sodium after operation.Coagulation function,visual analogue scale(VAS),leg circumference measurement and B-ultrasound of deep veins of lower extremities were carried out before and after surgery.Results:The difference of plasma D-dimer and fibrinogen concentration on the 7 th day after operation was statistically significant(P<0.05).VAS score:There was no statistically significant difference between the treatment group and the control group before and on the first day after surgery(P>0.05),and the differences on the 3 rd and 7 th day after surgery were statistically significant(P<0.01).Lower limb circumference value:The difference between the treatment group and the control group in the changes of thigh circumference and calf circumference after surgery was statistically significant(P<0.01).B-ultrasound of deep veins of lower extremities:There was no venous thrombosis of the lower extremities in the treatment group and the control group.The degree of improvement in the treatment group was significantly better than that in the control group.Conclusion:Activating blood and diuresis after total knee arthroplasty can effectively improve the blood hypercoagulability and quickly alleviated pain and limb swelling.
作者
卢建华
沈淑劲
储小兵
何帮剑
黄杰烽
杨扬
朱广奇
LU Jianhua;SHEN Shujin;CHU Xiaobing;HE Bangjian;HUANG Jiefeng;YANG Yang;ZHU Guangqi(The First Affiliated Hospital of Zhejiang Chinese Medical University,Hangzhou 310006,China;Zhejiang Tongxiang Traditional Chinese Medicine Hospital,Tongxiang 314500,Zhejiang China;Zhejiang Xiaoshan Hospital,Hangzhou 311200,China)
出处
《中国中医骨伤科杂志》
CAS
2022年第2期31-35,共5页
Chinese Journal of Traditional Medical Traumatology & Orthopedics
基金
浙江省中医药科学研究基金项目(2019ZB039)。
关键词
桃红四物汤
五苓散
全膝关节置换术
深静脉血栓
Taohong Siwu decoction
Wuling san
total knee arthroplasty
deep vein thrombosis
