摘要
目的探讨妊娠晚期使用前列腺素制剂引产对新生儿黄疸的影响。方法收集米索前列醇引产产妇30例(A组)、普贝生引产产妇30例(B组),自然临产产妇30例(C组)作为研究对象,测定3组新生儿在产后24、48、72 h的经皮胆红素水平,比较米索前列醇引产组、普贝生引产组与自然临产组在三个不同时段的新生儿经皮胆红素水平。当经皮胆红素水平>220.6μmol/L时,抽取新生儿静脉血测定丙氨酸氨基转移酶、天门冬氨酸氨基转移酶以及胆红素水平,比较新生儿黄疸的发生率。结果米索前列醇引产组与自然临产组新生儿经皮胆红素水平在产后24、48、72 h比较差异无统计学意义(P>0.05);2组新生儿黄疸发生率差异无统计学意义(P>0.05)。普贝生引产组与自然临产组新生儿经皮胆红素水平在产后24、48、72 h比较,差异无统计学意义(P>0.05),2组新生儿黄疸发生率差异无统计学意义(P>0.05)。结论妊娠晚期使用前列腺素制剂引产不会增加新生儿胆红素水平及新生儿黄疸发生率,前列腺素制剂引产与新生儿黄疸无明显相关性。
Objective To investigate the effects of induced labor by prostaglandin preparation on neonatal jaundice in late pregnancy.Methods A total of 30 parturients who underwent induced labor by prostaglandin(group A),30 parturients who 30 parturients who underwent induced labor by Propess(group B),and 30 parturients who underwent spontaneous delivery(group C)were enrolled in the study.The percutaneous bilirubin levels of neonates at 24h,48h and 72h after delivery were detected and compared among the three groups.When the percutaneous bilirubin levels exceeded 220.6μmol/L,the neonatal venous blood specimens were taken to measure the levels of alanine aminotransferase,glutamic-oxalacetic aminotransferase and bilirubin,moreover,the incidence of neonatal jaundice was observed and compared among the three groups.Results There were no significant differences in the percutaneous bilirubin levels of neonates at 24h,48h and 72h after delivery as well as the incidence of neonatal jaundice between group A and group C(P>0.05).There were no significant differences in the percutaneous bilirubin levels of neonates at 24h,48h and 72h after delivery as well as the incidence of neonatal jaundice between group B and group C(P>0.05).Conclusion The induced labor by prostaglandin preparation in late pregnancy does not increase the levels of bilirubin and the incidence of neonatal jaundice,and there is no obvious correlation between induced labor by prostaglandin preparation and the incidence of neonatal jaundice.
作者
刘艳慧
娄玉芹
马向英
吕英璞
LIU Yanhui;LOU Yuqin;MA Xiangying(Department of Obstetrics and gynecology,Shijiazhuang People’s Hospital,Hebei,Shijiazhuang 050000,China)
出处
《河北医药》
CAS
2022年第6期905-908,共4页
Hebei Medical Journal
基金
石家庄市科学技术研究与发展计划(编号:181460693)。
关键词
前列腺素制剂
引产
新生儿黄疸
prostaglandin preparations
induced labor
neonatal jaundice
