摘要
作为从天然植物中提取的活性成分,中药精油具有广泛的药理活性,在医药、食品、化妆品以及农业等方面应用广泛。然而大多数精油主要成分均为挥发性成分,其受光、热、湿及氧气等影响稳定性很差,易挥发、氧化分解及异构化等,导致精油生物活性下降甚至产生毒副产物。如何通过制剂技术解决中药精油稳定性差的问题,以保护其活性成分,成为制约其储存及应用的一大挑战。纳米制剂技术为改善中药精油的稳定性提供了一种有效的方法,为此综述了纳米制剂技术改善中药精油稳定性的研究进展与存在问题,以期为中药精油的制剂稳定化应用提供参考。
As the effective components extracted from the natural plants, the essential oils from traditional Chinese medicine have some biological effects and are widely used in medicine, food, cosmetics, and agriculture industries. However, the main components of most essential oils are volatile components, and the stability of exposure to light, heat, humidity and oxygen is very poor. The active components are volatile, oxidatively decomposed, and isomerized, which lead to the decrease of the biological activity of the essential oils and even the production of toxic by-products. How to solve the problem of poorly physical and chemical stability of essential oils through preparation methods has become an inevitable challenge for their storage and application. Nanotechnology provides an effective method for improving the stability of essential oils from traditional Chinese medicine. To this end, this article reviews the research progress and key issues of nanotechnology to improve the stability of essential oils from traditional Chinese medicine, in order to provide a reference for the formulation and application of essential oils from traditional Chinese medicine.
作者
赖华彰
陈水燕
周伟成
陈安琪
陈曦
陈颖翀
岳鹏飞
杨明
LAI Hua-zhang;CHEN Shui-yan;ZHOU Wei-cheng;CHEN An-qi;CHEN Xi;CHEN Ying-chong;YUE Peng-fei;YANG Ming(Key Laboratory of Modern Preparation of TCM,Ministry of Education,Jiangxi University of Chinese Medicine,Nanchang 330004,China)
出处
《中草药》
CAS
CSCD
北大核心
2022年第2期641-652,共12页
Chinese Traditional and Herbal Drugs
基金
国家自然科学基金面上项目(81974524)
江西省重大科技研发专项(20194ABC28009)
江西中医药大学研究生创新基金项目(JZYC21S33)。
关键词
纳米技术
核-壳型纳米载体
基质型纳米载体
中药精油
稳定性
nanotechnology
core-shell based nanocarrier
matrix based nanocarrier
essential oil of traditional Chinese medicine
stability
