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颅脑损伤后人型支原体颅内感染1例 被引量:2

One case of Mycoplasma hominis-related intracranial infection after craniocerebral injury
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摘要 患者,50岁男性,2020年4月1日以“高处坠落致志不清伴呕吐1 h”为主诉入院,拟急诊行“开颅减压术”。术后3 d出现间歇性发热,最高38℃,血液标本炎症指标均高于参考值上限,经验性抗感染治疗,仍反复发热。4月12日患者脑脊液标本常规与生化检测指标提示颅内感染,予以万古霉素联合美罗培南治疗。脑脊液与血液标本培养48 h后,见针尖样、透明小菌落生长,经16S rRNA基因鉴定结果为人型支原体。患者最终因病情严重且并发症多,治疗无效判定死亡。 The patient,a 50-year-old male,was admitted to the hospital on April 1,2020 with the chief complaint of"confusion with vomiting for 1 hour due to falling from height",and the emergency craniotomy was performed.Intermittent fever with a maximum temperature of 38℃occurred 3 days after the surgery,and the inflammation indexes were all higher than the upper limit of the reference values.Recurrent fever remained despite after empirical anti-infection treatment.On April 12,the patient was treated with vancomycin combined with meropenem after cerebrospinal fluid specimens routine and biochemical tests suggested intracranial infection.After 48 hours of cultivating the cerebrospinal fluid and blood specimens,some small,clear,needle-like colonies were found and they were identified as Mycoplasma humanum by using 16S rRNA gene.Eventually,the patient died due to the severity of the disease and complications.
作者 陈丽娟 郑丽衡 林晶 黄雪 Chen Lijuan;Zheng Liheng;Lin Jing;Huang Xue(Department of Laboratory,Xianyou County General Hospital,Putian 351254,China)
出处 《中华检验医学杂志》 CAS CSCD 北大核心 2022年第2期197-199,共3页 Chinese Journal of Laboratory Medicine
关键词 支原体 人型 颅脑损伤 感染 Mycoplasma hominis Craniocerebral trauma Infection
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