摘要
儿童肝功能异常病因复杂,食物过敏可以引起肝脏免疫性损伤,是儿童肝功能异常的原因之一,其临床常表现为高转氨酶血症,大多无胆汁淤积及肝脏肿大。排除其他常见的肝功能异常病因后,食物回避激发试验观察转氨酶的变化,可以用于诊断食物过敏相关肝损伤。该文就食物过敏相关肝功能异常的研究现状、潜在机制及临床特点作一综述,旨在提高临床医师对该现象的认识,更好地进行疾病诊治。
The etiology of abnormal liver function in children is complex.Food allergy can cause liver immunity injury,which is one of the causes of abnormal liver function in children.The common clinical manifestation is hypertransaminasemia,mostly without cholestasis and hepatomegaly.After the exclusion of common causes of abnormal liver function,food challenge test to observe the changes of transaminase is used to diagnose abnormal liver function related to food allergy.This article reviews the research status,potential mechanism and clinical characteristic of abnormal liver function related to food allergy,aiming to improve the understanding of the phenomenon of clinicians,and better diagnosis and treatment of the disease.
作者
陈凡(综述)
舒赛男(审校)
Chen Fan;Shu Sainan(Department of Pediatrics,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China)
出处
《国际儿科学杂志》
2022年第1期15-18,共4页
International Journal of Pediatrics
关键词
儿童
肝功能异常
食物过敏
乳糜泻
Child
Abnormal liver function
Food allergy
Celiac disease
