摘要
儿童良性癫痫伴中央颞区棘波(BECTS)是儿童期最常见的局灶性癫痫综合征。BECTS的发病涉及复杂多基因与环境因素相互作用,呈多因素遗传模式。BECTS病程中可演变为BECTS变异型,二者均可合并睡眠期癫痫性电持续状态(ESES)。BECTS的治疗需要考虑多种因素,进行个体化风险效益评估,以确定最佳治疗方案。应重视早期识别诊断BECTS患儿共患认知功能损害。注意缺陷多动障碍(ADHD)是BECTS儿童最常见的心理行为共患病。BECTS共患ADHD应尽早开始正规治疗。BECTS的临床诊疗依然存在困惑和挑战,文章介绍近年来该病诊治的相关研究进展,旨在为BECTS的临床诊疗提供参考,以提高患儿生活质量。
Benign epilepsy of childhood with centrotemporal spikes(BECT)is the commonest focal epilepsy syndrome in children.The pathogenesis of BECTS involves the interaction of complex polygenes and environmental factors,presenting a pattern of multifactorial inheritance.BECTS can evolve into atypical BECTS,both of which can be combined with electrical status epilepticus during slow wave sleep(ESES).The treatment of BECTS requires consideration of multiple factors and individualized risk-benefit assessment to determine the best treatment regimen.Early recognition and diagnosis of BECTS comorbid cognitive impairment should be emphasized.Attention deficit hyperactivity disorder(ADHD)is the commonest childhood psychobehavioral comorbidity of BECTS.Formal treatment of BECTS comorbid ADHD should be initiated as soon as possible.There are still many problems and challenges in the clinical diagnosis and treatment of BECTS.This article will review the recent progress in the diagnosis and treatment of BECTS,aiming to provide reference for the clinical diagnosis and treatment of BECTS and improve the life quality of children with BECTS.
作者
范玉颖
刘雪雁
王华
FAN Yuying;LIU Xueyan;WANG Hua(Department of Pediatrics,Shengjing Hospital of China Medical University,Shenyang 110004,Liaoning,China)
出处
《临床儿科杂志》
CAS
CSCD
北大核心
2022年第3期177-183,共7页
Journal of Clinical Pediatrics
基金
国家自然科学基金青年基金项目(No.81501299)
中国医科大学附属盛京医院345人才工程项目。
关键词
儿童良性癫痫伴中央颞区棘波
诊断
治疗
共患病
benign epilepsy of childhood with centrotemporal spikes
diagnosis
treatment
comorbidity
