摘要
目的:分析胃肠间质瘤疾病特点,评价腹腔镜下手术治疗对患者手术情况的影响。方法:选择2018年12月~2019年9月本院诊治的82例胃肠间质瘤疾病患者,获得伦理委员会审核,结合手术方法进行开腹治疗、腹腔镜下手术治疗的对照组与观察组分组,各41例。比较2组胃肠间质瘤疾病患者的手术相关指标、术后应激指标水平以及并发症发生率、术后半年复发及转移情况、治疗效果满意度。结果:组间手术相关指标(手术时间、术中出血量、康复时间)比较,观察组胃肠间质瘤患者术中出血量少,手术与术后康复时间短,P<0.05;组间术后24h皮质醇(Cortisol,Cor)、白介素-1(Interleukin-1,IL-1)、肿瘤坏死因子-α(Tumor Necrosis Factor-α,TNF-α)应激指标水平比较,观察组胃肠间质瘤患者Cor、IL-1、TNF-α水平均明显低于对照组,P<0.05;组间术后随访复发及转移情况比较,差异不明显,P>0.05;组间术后感染、粘连性肠梗阻等并发症情况比较,观察组发生率(7.31%)明显低于对照组,P<0.05;治疗效果满意度比较,观察组满意度明显高于对照组,P<0.05。结论:开腹、腹腔镜下手术治疗胃肠间质瘤远期效果接近,而后者腹腔镜下手术治疗在手术创伤、术后恢复、安全性方面更具优势,患者满意度高。
Objective:To analyze the characteristics of gastrointestinal stromal tumors and evaluate the impact of laparoscopic surgery on patients’surgical conditions.Methods:A total of 82 patients with gastrointestinal stromal tumor disease diagnosed and treated in our hospital from December 2018 to September 2019 were selected and divided into the control group and the observation group,41 cases in each group,who were audited by the ethics committee and underwent laparotomy and laparoscopic surgery combined with surgical methods.Compared the two groups of patients with gastrointestinal stromal tumor disease operation related indicators,postoperative stress index level,complication rate,recurrence and metastasis six months after surgery,treatment effect satisfaction.Results:The comparison of operation related indexes(operation time,intraoperative blood loss and recovery time)between groups showed that the observation group had less intraoperative blood loss and shorter operation and postoperative recovery time(P<0.05).After 24 hours,the levels of stress indexes of cortisol(Cortisol,Cor),interleukin-1(Interleukin-1,IL-1)and tumor necrosis factor-α(TNF-α)in the observation group were compared.The levels of Cor,IL-1 and TNF-αin patients with plasmoma were significantly lower than those in the control group,P<0.05;The postoperative follow-up recurrence and metastasis between the groups showed no significant difference,P>0.05.Comparing the postoperative infection,adhesive intestinal obstruction and other complications between the groups,the incidence rate of the observation group(7.31%)was significantly lower than that of the control group,P<0.05.Conclusion:The long-term effect of laparotomy and laparoscopic surgery in the treatment of gastrointestinal stromal tumor is similar,while laparoscopic surgery has more advantages in surgical trauma,postoperative recovery,safety and high patient satisfaction.
作者
王鹤峰
WANG He-feng(Department of General Surgery,Dandong Central Hospital,Liaoning Dandong 118000)
出处
《中国医疗器械信息》
2022年第3期116-118,共3页
China Medical Device Information
关键词
腹腔镜手术
胃肠间质瘤
术后并发症
手术指标
应激指标水平
复发及转移情况
laparoscopic surgery
gastrointestinal stromal tumors
postoperative complications
surgical indicators
stress indicator levels
recurrence and metastasis
