摘要
目的了解维持性血液透析(maintenance hemodialysis,MHD)患者衰弱发生的情况,并探讨MHD患者衰弱的相关性及其影响因素,进而为MHD患者衰弱的干预提供一定的依据。方法选择2021年1月-3月在四川大学华西医院肾脏内科行MHD的患者。采用Frail量表及匹兹堡睡眠质量指数(Pittsburgh Sleep Quality Index,PSQI)量表对其进行评估及问卷调查,并分析MHD患者衰弱的影响因素及其与衰弱的相关性。结果共纳入MHD患者141例,其中无衰弱57例(40.43%),衰弱前期71例(50.35%),衰弱13例(9.22%);睡眠质量很好54例(38.30%),睡眠质量较好56例(39.72%),睡眠质量一般24例(17.02%),睡眠质量很差7例(4.96%)。MHD患者衰弱与年龄(r;=0.265,P=0.002)、PSQI(r;=0.235,P=0.005)、镁(rs=0.280,P=0.001)呈正相关。Logistic回归分析结果显示,MHD患者衰弱的影响因素为性别[比值比(odds ratio,OR)=4.321,95%置信区间(confidence interval,CI)(1.525,12.243),P=0.006]、PSQI[OR=1.110,95%CI(1.009,1.222),P=0.032]、镁[OR=122.072,95%CI(4.752,3135.528),P=0.004]、高血压[OR=0.112,95%CI(0.023,0.545),P=0.007]、其他疾病[OR=0.102,95%CI(0.019,0.552),P=0.008]。结论MHD患者衰弱发生率高,性别、PSQI、镁、高血压、其他疾病是MHD患者衰弱的影响因素,且衰弱和睡眠呈相关性。建议肾科医务人员应多关注MHD衰弱与睡眠的评估,联合多学科进行个性化干预,以提高MHD患者生活质量。
Objective To understand the incidence of frailty in maintenance hemodialysis(MHD)patients,and to explore the correlation and influencing factors of frailty in MHD patients,so as to provide some basis for the intervention of frailty in MHD patients.Methods Patients who underwent MHD in the Department of Nephrology of West China Hospital of Sichuan University from January to March 2021 were selected.Frail scale and Pittsburgh Sleep Quality Index(PSQI)were used for evaluation,and the influencing factors of frail in patients with MHD and its correlation with frail were analyzed.Results A total of 141 patients with MHD were included,including 57 cases without frailty(40.43%),71 cases in early frailty(50.35%),and 13 cases in frailty(9.22%).54 cases(38.30%)had very good sleep quality,56 cases(39.72%)had good sleep quality,24 cases(17.02%)had average sleep quality,and 7 cases(4.96%)had very poor sleep quality.The frailty of MHD patients was positively correlated with age(r;=0.265,P=0.002),PSQI(rs=0.235,P=0.005)and magnesium(r;=0.280,P=0.001).Logistic regression analysis showed that the influencing factors of MHD patients’frailty were gender[odds ratio(OR)=4.321,95%confidence interval(CI)(1.525,12.243),P=0.006],PSQI[OR=1.110,95%CI(1.009,1.222),P=0.032],magnesium[OR=122.072,95%CI(4.752,3135.528),P=0.004],hypertension[OR=0.112,95%CI(0.023,0.545),P=0.007]and other diseases[OR=0.102,95%CI(0.019,0.552),P=0.008].Conclusions The incidence of frailty in MHD patients is high.Gender,PSQI,magnesium,hypertension and other diseases are the influencing factors of frailty in MHD patients,and there is a correlation between frailty and sleep.It is suggested that renal medical staff should pay more attention to the assessment of MHD frailty and sleep,and carry out multi-disciplinary personalized intervention to improve the quality of life of MHD patients.
作者
高梦琳
曾英
王雪
杨玉洁
袁怀红
GAO Menglin;ZENG Ying;WANG Xue;YANG Yujie;YUAN Huaihong(Department of Nephrology,West China Hospital,Sichuan University/West China School of Nursing,Sichuan University,Chengdu,Sichuan 610041,P.R.China)
出处
《华西医学》
CAS
2022年第2期242-247,共6页
West China Medical Journal
基金
四川省科学技术厅科普培训项目(2021JDKP0084)。
关键词
维持性血液透析
匹兹堡睡眠质量指数
衰弱
影响因素
相关性
Maintenance hemodialysis
Pittsburgh Sleep Quality Index
frail
influencing factors
correlation
