摘要
目的探讨骨髓细胞形态学诊断中噬血细胞增多的临床价值。方法选取2017年6月至2019年6月本院收治的噬血细胞性淋巴组织细胞增多症(HLH)患者110例作为研究对象,对其进行骨髓细胞形态学检验,分析凝血功能和血液细胞功能。结果110例患者骨髓涂片检验显示,骨髓内的核细胞增生活跃,巨核细胞、红细胞、粒细胞明显升高;巨核细胞多见颗粒型,形态不规则,胞浆丰富,涂片内可见大量噬血细胞。血液细胞检查发现,110例HLH患者存在程度不等的全血细胞减少情况者,占比77.27%(85/110),经凝血功能检验,凝血功能障碍者109例,占比99.09%(109/110)。结论骨髓细胞形态学诊断中噬血细胞增多的临床价值显著,值得临床借鉴。
Objective To investigate the clinical value of hemophagocytosis in the diagnosis of bone marrow cell morphology.Methods 110 patients with hemophagocytic lymphohistiocytosis(HLH)who were admitted to our hospital from June 2017 to June 2019 were selected as the research subjects,and the morphological examination of bone marrow cells was performed to analyze the coagulation function and blood cell function.Results Bone marrow smears of 110 patients showed that the proliferation of nuclear cells in bone marrow was active,and megakaryocytes,erythrocytes and granulocytes were significantly increased;most of megakaryocytes were granular,with irregular shape and abundant cytoplasm,and a large number of hemophagocytes were seen in the smears.The results of blood cell examination showed that 77.27%(85/110)of 110 HLH patients had pancytopenia of varying degrees.According to the blood coagulation function test,109 cases of HLH patients had coagulation dysfunction,accounting for 99.09%(109/110).Conclusion The clinical value of hemophagocytosis in the diagnosis of bone marrow cell morphology is significant,which can be used for clinical reference.
作者
徐秀艳
XU Xiuyan(The Third Affiliated Hospital of Shenyang Medical College(Shenyang 242 Hospital),Shenyang,Liaoning,110034,China)
出处
《当代医学》
2022年第6期72-74,共3页
Contemporary Medicine
关键词
骨髓细胞形态学
诊断
噬血细胞增多
凝血功能
血液细胞功能
Bone marrow cell morphology
Diagnosis
Hemophagocytosis
Coagulation function
Blood cell function
