摘要
目的观察25 G微创玻璃体切除联合内界膜翻转联合自体血清覆盖对高度近视性黄斑裂孔(HMMH)的疗效。方法选取2019年6月至2020年3月在新疆医科大学附属中医医院就诊的HMMH患者17例17眼,所有患者黄斑裂孔最小直径均≤500μm,按随机数字表法将其分为A、B两组,其中A组(10眼)行25 G玻璃体切除+内界膜翻转+自体血清覆盖,B组(7眼)行25 G玻璃体切割+内界膜撕除;观察两组术前术后最佳矫正视力(BCVA)及黄斑裂孔解剖闭合情况。结果两组术前BCVA及术后6个月时BCVA差异无统计学意义(P>0.05);A组术后黄斑裂孔闭合率为8/10,B组术后黄斑裂孔闭合率为4/7,两组间黄斑裂孔闭合率差异无统计学意义(P>0.05);两组术后末次随访BCVA均较术前显著提高,差异有统计学意义(P<0.05)。结论对于直径≤500μm的高度近视性黄斑裂孔,25 G微创玻切联合内界膜翻转联合自体血清覆盖是一种安全、有效的治疗方法,有一定的临床应用价值。
Objective To observe the treatment effect of 25-gauge pars plana vitretomy with the inverted internal limiting membrane(ILM)flap and autologous serum coverage in high myopia macular hole(HMMH)eyes.Methods 17 patients(17 eyes)with HMMH were selected from the Affiliated Hospital of Chinese Medicine Hospital of Xinjiang Medical University from June 2019 to March 2020.The minimum diameter of macular hole in all patients was≤500μm.They were diveded into group A(10 eyes)and group B(7 eyes)according to the random number table method.The group A underwent 25-gauge pars plana vitretomy+inverted ILM falp technique+autologous serum coverage;The group B(5 eyes)underwent 25-gauge pars plana vitretomy with ILM peeling technique.The best corrected visual acuity(BCVA)before and after surgey and the macualr hole closure rates were observed.Results There was no significant difference in BCVA between the two groups before operation and at 6 months after operation(P>0.05);The postoperative macular hole closure rate was 8/10 in group A and 4/7 in group B.There was no significant difference in macular hole closure rate between the two groups(P>0.05);The BCVA of the two groups at the last follow-up after operation was significantly higher than that before operation(P<0.05).Conclusions Vitrectomy combined with inverted ILM falp technique is a safe and effective method in the treatment of high myopia macular hole with diameter≤500μm.
作者
赵勇
阿依努・努拉厚
王雁
Zhao Yong;Ayinu Nulaho;Wang Yan(Department of Ophthalmology,Affiliated Chinese Medicine Hospital,Xinjiang Medical University,Urumqi 830000,China)
出处
《中国医师杂志》
CAS
2022年第1期19-23,共5页
Journal of Chinese Physician
基金
新疆维吾尔自治区自然科学基金(2019D01C176)。
关键词
玻璃体切除术
黄斑裂孔
内界膜翻转
内界膜撕除
自体血清
Vitrectomy
Macular holes
Internal limiting membrane flap
Internal limiting membrane peeling
Autologous serum
