摘要
目的探讨孕早期先兆流产患者血清激素水平、孕囊、胚芽与保胎结局的相关性。方法抽取太原钢铁(集团)有限公司总医院2018年1月至2020年12月收治的孕早期先兆流产患者54例,根据保胎结局分为流产组(21例)和继续妊娠组(33例)。比较两组患者不同停经周期的血清β-人绒毛膜促性腺激素(β-hCG)、雌二醇、孕酮水平,超声检查不同停经周期的孕囊和胚芽生长情况。结果停经6、7、8、9周时,继续妊娠组血清β-hCG、雌二醇、孕酮水平均高于流产组(P均<0.05)。停经6周时,继续妊娠组孕囊平均直径、胚芽平均长度与流产组比较,差异未见统计学意义(P>0.05);停经7、8、9周时,继续妊娠组孕囊平均直径、胚芽平均长度均大于流产组(P均<0.05)。结论实时监测孕早期先兆流产患者血清β-hCG、雌二醇、孕酮水平,并超声动态监测孕囊和胚芽生长情况,对预判保胎结局有一定价值。
Objective To investigate the correlation of serum hormone level,gestational sac,embryo with abortion outcome in patients with threatened abortion in early pregnancy.Methods Fifty-four patients with threatened abortion in early pregnancy admitted to General Hospital of Taiyuan Iron and Steel(Group)Co.,Ltd.from January 2018 to December 2020 were selected.According to the outcomes of abortion,they were divided into abortion group(21 cases)and continued pregnancy group(33 cases).The levels of serumβ-human chorionic gonadotropin(β-hCG),estradiol and progesterone in different menopause cycles were compared between the two groups.The growth of gestational sac and embryo in different menopause cycles were detected by ultrasound examination.Results The levels of serumβ-hCG,estradiol and progesterone in continued pregnancy group were higher than those in abortion group at 6,7,8 and 9 weeks after menopause(P<0.05).At 6 weeks after menopause,there was no significant difference in the average diameter of gestational sac and the average length of embryo between the continuing pregnancy group and the abortion group(P>0.05).At 7,8 and 9 weeks after menopause,the average diameter of gestational sac and the average length of embryo in the continued pregnancy group were higher than those in the abortion group(all P<0.05).Conclusions For patients with threatened abortion in early pregnancy,real-time monitoring of serum levels ofβ-hCG,estradiol and progesterone,and dynamic monitoring of gestational sac and embryo growth by ultrasound can accurately predict the outcome of fetal protection.
作者
孟渊
Meng Yuan(Department of Ultrasound,General Hospital of Taiyuan Iron and Steel(Group)Co.,Ltd.,Taiyuan 030027,China)
出处
《中国实用医刊》
2021年第23期60-63,共4页
Chinese Journal of Practical Medicine
关键词
先兆流产
Β-人绒毛膜促性腺激素
雌二醇
孕酮
孕囊
胚芽
Abortion,threatened
β-human chorionic gonadotropin
Estradiol
Progesterone
Pregnancy sac
Embryo