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交联透明质酸钠凝胶联合仿生物电刺激预防人工流产术后宫腔粘连疗效 被引量:17

Effect of cross-linked sodium hyaluronate gel combined with biomimetic electrical stimulation used in women for preventing their intrauterine adhesions after abortion
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摘要 目的:分析宫腔用交联透明质酸钠凝胶联合仿生物电刺激预防人工流产术后宫腔粘连疗效。方法:前瞻性选择2019年12月-2020年12月本院行人工流产者86例按照交替分组法分组,两组均接受宫腔用交联透明质酸钠凝胶治疗,观察组加用仿生物电刺激治疗。对比两组临床疗效,术后1个月宫腔粘连,术后1、2、3周时子宫内膜厚度以及并发症发生情况。结果:观察组阴道流血量(37.2±3.6ml)、月经复潮(28.3±2.3d)及阴道出血时间(2.6±1.1 d)均少于对照组(48.3±5.5ml、35.2±2.3 d、3.8±1.2 d)(P<0.05);两组术后1周子宫内膜厚度无差异,术后2周、3周时子宫内膜厚度两组均大于术后1周且观察组(7.24±0.41 mm、9.85±0.18 mm)大于对照组(6.03±0.26 mm、7.42±0.30 mm)(P<0.05);宫腔粘连发生率观察组(2.3%)低于对照组(16.3%)(P<0.05),术后并发症发生率观察组(18.6%)与对照组(7.0%)无差异(P>0.05)。结论:宫腔用交联透明质酸钠凝胶联合仿生物电刺激可缩短受术者术后恢复时间,增加子宫内膜厚度,降低宫腔粘连发生率。 Objective:To analyze the effect of cross-linked sodium hyaluronate gel combined with biomimetic electrical stimulation used in women for preventing their intrauterine adhesions after abortion.Methods:86 women who underwent abortion were prospectively selected and were divided in two groups according to the alternate grouping method from December 2019 to December 2020.The women in the control group had received intrauterine treatment with cross-linked sodium hyaluronate gel,and the women in the observation group were treated with cross-linked sodium hyaluronate gel combined with biomimetic electrical stimulation.The clinical efficacy and the postoperative recovery,the intrauterine adhesions situation in 1 month after abortion,the endometrial thickness in 1,2 and 3 weeks after abortion,and postoperative complications rate of the women were compared between the two groups.Results:The amount of vaginal bleeding(37.2±3.6ml),the time of menstrual recovery(28.3±2.3d),and the vaginal bleeding time(2.6±1.1 d)of the women in the observation group were significantly lower than those(48.3±5.5ml,35.2±2.3 d,and 3.8±1.2 d)of the women in the control group(P<0.05).There was no significant difference in the endometrial thickness of the women in 1 week after abortion between the two groups.The endometrial thickness of the women in the two group in 2 or 3 weeks after abortion was significantly higher that of the women in 1 week after abortion,and which(7.24±0.41 mm or 9.85±0.18 mm)of the women in 2 or 3 weeks after abortion in the observation group was significantly higher than that(6.03±0.26 mm or 7.42±0.30 mm)of the women in the control group(P<0.05).The incidence of intrauterine adhesion(2.3%)of the women in the observation group was significantly lower than that(16.3%)of the women in the control group(P<0.05),and there was no significant difference in the incidence of postoperative complications(18.6%vs.7.0%)of the women between the two groups(P>0.05).Conclusion:Intrauterine treatment of cross-linked sodium hyaluronat
作者 闫彩平 朱玲娜 李宗涛 邓鹏飞 YAN Caiping;ZHU Lingna;LI Zongtao;DENG Pengfei(Zhuhai People 's Hospital, Guangdong Province, 519000)
出处 《中国计划生育学杂志》 2021年第12期2620-2622,共3页 Chinese Journal of Family Planning
关键词 人工流产术 预防宫腔粘连 宫腔用交联透明质酸钠凝胶 仿生物电刺激 术后恢复 Abortion Prevention of intrauterine adhesions Intrauterine treatment of cross-linked sodium hyaluronate gel Bioelectrical stimulation Postoperative recovery
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