摘要
以2,5-二氢呋喃为原料,N,N-二乙基羟胺为阻聚剂,在羰基氯氢三(三苯基膦)钌催化下进行加压反应制备中间体2,3-二氢呋喃;然后采用以纳米催化剂ZrO_(2)/TiO_(2)/γ-酸性氧化铝的固定床催化工艺,高效异构化制备环丙甲醛,两步反应总收率达75.0%以上。研究了环丙甲醛的工业化生产工艺,考察了多种稀有金属催化剂、反应温度、压力和阻聚剂的类型及用量等因素对合成2,3-二氢呋喃的影响,并对固定床催化工艺的反应温度和催化剂进行了筛选。
The intermediate 2,3-dihydrofuran was prepared in high yield with good selectivity using2,5-dihydrofuran as raw material,N,N-diethylhydroxylamine as a polymerization inhibitor,under pressure reaction catalyzed by carbonyl tris(triphenylphosphine)ruthenium.Then,2,3-dihydrofuran was efficiently isomerized to cyclopropanaldehyde in a fixed-bed process catalyzed by the nano-catalyst ZrO_(2)/TiO_(2)/γ-acidic alumina.The total yield of the two-step reaction is over 75.0%.The industrial production methods of cyclopropanaldehyde were studied.The effects of various rare metal catalysts,reaction temperature,pressure,and the type and amount of polymerization inhibitors on the synthesis of 2,3-dihydrofuran were investigated,Similarly,the effects of reaction temperature of the fixed-bed catalytic process and composite of catalysts on the synthesis of cyclopropanaldehyde have also been investigated.With the advantages of green and high efficiency,this process has broad market prospects.
作者
黄朋勉
吕彦博
赵东江
彭鹏
王梓鉴
刘祥威
黄超群
Huang Pengmian;Lv Yanbo;Zhao Dongjiang;Peng Peng;Wang Zijian;Liu Xiangwei;Huang Chaoqun(School of Chemistry and Chemical Engineering, Changsha University of Science and Technology, Changsha 410000, Hu’nan, China;Changsha Jiaqiao Biotechnology Limited Company, Changsha 410000, Hu’nan, China)
出处
《精细石油化工》
CAS
2022年第1期23-27,共5页
Speciality Petrochemicals
基金
湖南省教育厅资助科研项目(20A019)
湖南省水生资源食品加工工程技术研究中心开放基金项目资助(2018KJY08)
湖南省研究生科研创新项目(CX20200889)。
关键词
2
5-二氢呋喃
2
3-二氢呋喃
环丙甲醛
异构化
阻聚剂
2,5-dihydrofuran
2,3-dihydrofuran
cyclopropanaldehyde
isomerization
polymerizationinhibitor
