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早期与延迟经皮椎体成形术治疗症状性胸腰椎骨质疏松性椎体压缩性骨折 被引量:20

Early and delayed percutaneous vertebroplasty for symptomatic thoracolumbar osteoporotic vertebral compression fracture
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摘要 目的评价早期与延迟经皮椎体成形术(PVP)治疗症状性胸腰椎骨质疏松性椎体压缩性骨折(OVCF)的临床疗效。方法回顾性分析2016年6月—2019年2月在清华大学第一附属医院接受PVP治疗的60例症状性胸腰椎OVCF患者资料,根据手术时机分为早期治疗组(n=32,从发现典型症状到采取手术治疗的时间<3周)和延迟治疗组(n=28,从发现典型症状到采取手术治疗的时间≥3周)。记录2组患者一般资料,采用疼痛视觉模拟量表(VAS)评分和Oswestry功能障碍指数(ODI)评估手术疗效,记录术中及术后并发症发生情况。结果所有手术顺利完成。所有患者随访超过6个月。2组患者术后VAS评分和ODI均较术前显著改善,差异有统计学意义(P<0.05);组间差异无统计学意义(P>0.05)。早期治疗组和延迟治疗组分别有5例(15.6%)和6例(21.4%)发生骨水泥渗漏,组间差异无统计学意义(P>0.05);早期治疗组和延迟治疗组分别有1例(3.1%)和4例(14.3%)发生椎体再骨折,组间差异无统计学意义(P>0.05)。结论早期与延迟PVP治疗症状性胸腰椎OVCF均有较好的临床疗效。 Objective To evaluate the clinical efficacy of early and delayed percutaneous vertebroplasty(PVP)in the treatment of smptomatic thoracolumbar osteoporotic vertebral compression fractures(OVCF).Methods The data of 60 symptomatic thoracolumbar OVCF patients treated with PVP in the First Affiliated Hospital of Tsinghua University from June 2016 to February 2019 were retrospectively analyzed.According to the timing of operation,patients were divided into early treatment group(n=32,the time from finding typical symptoms to surgical treatment<3 weeks)and delayed treatment group(n=28,the time from finding typical symptoms to surgical treatment≥3 weeks).The general information of 2 groups were recorded.The visual analogue scale(VAS)score and the Oswestry disability index(ODI)were used to assess the outcome.The intraoperative and postoperative complications were recorded.Results All the operations were successfully completed.All the patients were followed up for more than 6 months.The VAS score and ODI of the 2 groups were significantly improved after operation compared with pre-operation,and the differences were statistically significant(P<0.05);but there was no significant difference between the 2 groups(P>0.05).There were 5 cases(15.6%)in the early treatment group and 6(21.4%)in the delayed treatment group with bone cement leakage,and there was no significant difference between the 2 groups(P>0.05).There was 1(3.1%)in the early treatment group and 4(14.3%)in the delayed treatment group with vertebral refracture,and there was no significant difference between the 2 groups(P>0.05).Conclusion Both early and delayed PVP are effective in the treatment of symptomatic thoracolumbar OVCF.
作者 徐建彪 梁宁 王占长 Xu Jianbiao;Liang Ning;Wang Zhanchang(Department of Orthopaedics,First Affiliated Hospital of Tsinghua University,Beijing 100016,China;School of Clinical Medicine,Tsinghua University,Beijing 100084,China)
出处 《脊柱外科杂志》 2022年第1期22-26,共5页 Journal of Spinal Surgery
关键词 胸椎 腰椎 骨折 压缩性 骨质疏松 椎体成形术 Thoracic vertebrae Lumbar vertebrae Fractures,compression Osteoporosis Vertebroplasty
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